Evaluation of high-throughput genomic assays for the Fc Gamma Receptor Locus

Evaluation of high-throughput genomic assays for the Fc Gamma Receptor Locus

Cancer immunotherapy has been revolutionised by the use monoclonal antibodies (mAb) that function through their interaction with Fc gamma receptors (Fc?Rs). The low-affinity Fc?R genes are highly homologous, map to a complex locus at 1p23 and harbour single nucleotide polymorphisms (SNPs) and copy...

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Main Authors: Hargreaves, Chantal (Author), Iriyama, C. (Author), Rose-Zerilli, Matthew (Author), Nagelkerke, S.Q (Author), Hussain, Khiyam (Author), Ganderton, R. (Author), Lee, C. (Author), Kuijpers, T.W (Author), Potter, Nora (Author), Coupland, S. (Author), Davies, Andrew (Author), Stackpole, M. (Author), Oates, M. (Author), Pettitt, A.R (Author), Glennie, Martin (Author), Cragg, Mark (Author), Strefford, Jon (Author)
Format: Article
Language:English
Published: 2015-11-06.
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