Evidence for successive peptide binding and quality control stages during MHC class I assembly
Intracellular antigens are continually presented to cytotoxic T lymphocytes by major histocompatibility complex (MHC) class I molecules, which consist of a polymorphic 43 kDa heavy chain and a 12 kDa soluble subunit beta 2-microglobulin (beta 2m), and which bind an 8-10 amino-acid antigenic peptide....
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
1998-06-04.
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| Subjects: | |
| Online Access: | Get fulltext |