Relationship between pulmonary matrix metalloproteinases and quantitative CT markers of small airways disease and emphysema in COPD

Background Matrix metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and drive tissue remodelling, key processes in the pathogenesis of COPD. The development of small airway disease has been identified as a critical mechanism in the early development of airfl...

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Main Authors: Ostridge, Kristoffer (Author), Williams, Nicholas (Author), Kim, Viktoriya (Author), Bennett, Michael (Author), Harden, Stephen (Author), Welch, Lindsay (Author), Bourne, Simon (Author), Coombs, Ngaire A. (Author), Elkington, Paul T. (Author), Staples, Karl J. (Author), Wilkinson, Tom M.A (Author)
Format: Article
Language:English
Published: 2016-02.
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