A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma

A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma

Dysregulated expression of factors that control protein synthesis is associated with poor prognosis of many cancers, but the underlying mechanisms are not well defined. Analysis of the diffuse large B-cell lymphoma (DLBCL) translatome revealed selective upregulation of mRNAs encoding anti-apoptotic...

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Main Authors: Horvilleur, E. (Author), Sbarrato, T. (Author), Hill, K. (Author), Spriggs, R.V (Author), Screen, M. (Author), Goodrem, P.J (Author), Sawicka, K. (Author), Chaplin, L.C (Author), Touriol, C. (Author), Packham, G. (Author), Potter, K.N (Author), Dirnhofer, S. (Author), Tzankov, A. (Author), Dyer, M.J.S (Author), Bushell, M. (Author), MacFarlane, M. (Author), Willis, A.E (Author)
Format: Article
Language:English
Published: 2014-05.
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