Toll-like receptor 7 is reduced in severe asthma and linked to altered microRNA profile

RATIONALE:Asthma is one of the commonest chronic diseases worldwide and severe asthma sufferers experience recurrent exacerbations. Exacerbations are predominantly viral-associated and have been linked to defective airway interferon responses. Ascertaining the molecular mechanisms underlying this de...

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Main Authors: Rupani, Hitasha (Author), Martinez-Nunez, Rocio Teresa (Author), Dennison, Patrick (Author), Lau, Laurie (Author), Jayasekera, Nivenka (Author), Havelock, Tom (Author), Francisco-Garcia, Ana (Author), Grainge, Chris (Author), Howarth, Peter (Author), Sanchez-Elsner, Tilman (Author)
Format: Article
Language:English
Published: 2016-07.
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