IL-4 receptor alpha is an important modulator of IL-4 and IL-13 receptor binding: implications for the development of therapeutic targets
<p>IL-4 is a key cytokine associated with allergy and asthma. Induction of cell signaling by IL-4 involves interaction with its cognate receptors, a complex of IL-4Ralpha with either the common gamma-chain or the IL-13R chain alpha1 (IL-13Ralpha1). We found that IL-4 bound to the extracellular...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2006-06-15.
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| Subjects: | |
| Online Access: | Get fulltext |