The direct effect of nuclear pores on nuclear chemotherapeutic concentration in multi-drug resistant bladder cancer: the nuclear sparing phenomenon
Purpose: multidrug resistance commonly limits effectiveness in treating malignancy with chemotherapy. Multidrug resistance has classically been described as a cell membrane phenomenon. Multidrug resistant cells are known to specifically exclude chemotherapy from the nucleus, resulting in lower nucle...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2007-04.
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| Subjects: | |
| Online Access: | Get fulltext |