An antigen-specific pathway for CD8 T cells across the blood-brain barrier

CD8 T cells are nature's foremost defense in encephalitis and brain tumors. Antigen-specific CD8 T cells need to enter the brain to exert their beneficial effects. On the other hand, traffic of CD8 T cells specific for neural antigen may trigger autoimmune diseases like multiple sclerosis. T ce...

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Bibliographic Details
Main Authors: Galea, Ian (Author), Bernardes-Silva, Martine (Author), Forse, Penny A. (Author), van Rooijen, Nico (Author), Liblau, Roland S. (Author), Perry, V. Hugh (Author)
Format: Article
Language:English
Published: 2007-09-03.
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