Dissection of the functional interaction between p53 and the embryonic proto-oncoprotein PAX3
Studies from murine embryogenesis and cancer cells derived from human melanomas have identified a critical role for the transcription factor PAX3 in the suppression of p53 protein accumulation and p53-dependent apoptosis. Here we show, using a well-defined over-expression system, that PAX3 suppresse...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2007-12-22.
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| Subjects: | |
| Online Access: | Get fulltext |