FLAP inhibitors for the treatment of inflammatory diseases
Leukotrienes are lipid inflammatory mediators that are implicated in asthma, COPD, arthritis, cardiovascular disease and cancer. Leukotriene synthesis requires 5-lipoxygenase activating protein (FLAP), which acts as a scaffolding protein for the assembly of other enzymes involved in the leukotriene...
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Format: | Article |
Language: | English |
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2009-11.
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Online Access: | Get fulltext |