Differential effects of two-pore channel protein 1 and 2 silencing in MDA-MB-468 breast cancer cells

Two-pore channel proteins, TPC1 and TPC2, are calcium permeable ion channels found localized to the membranes of endolysosomal calcium stores. There is increasing interest in the role of TPC-mediated intracellular signaling in various pathologies; however their role in breast cancer has not been ext...

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Bibliographic Details
Main Authors: Jahidin, AH (Author), Monteith, GR (Author), Roberts-Thomson, SJ (Author), Stewart, TA (Author), Thompson, EW (Author)
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:View Fulltext in Publisher