Inhibition of prostaglandin E-2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation
The discovery of potent inhibitors of prostaglandin E-2 (PGE(2)) synthesis in recent years has been proven to be an important game changer in pharmaceutical industry. It is known that excessive production of PGE(2) triggers a vast array of biological signals and physiological events that contributes...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Online Access: | View Fulltext in Publisher |