CYP2D6 Genetic Polymorphisms and Phenotypes in Different Ethnicities of Malaysian Breast Cancer Patients

The cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) is an enzyme that is predominantly involved in the metabolism of tamoxifen. Genetic polymorphisms of the CYP2D6 gene may contribute to inter-individual variability in tamoxifen metabolism, which leads to the differences in clinical r...

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Bibliographic Details
Main Authors: Akmal, SN (Author), Chan, SC (Author), Chin, FW (Author), Rahman, SA (Author), Rosli, R (Author)
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:View Fulltext in Publisher