Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway

BackgroundMethanol extract (MECN) of Clinacanthus nutans Lindau leaves (family Acanthaceae) demonstrated peripherally and centrally mediated antinociceptive activity via the modulation of opioid/NO-mediated, but cGMP-independentpathway. In the present study, MECN was sequentially partitioned to obta...

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Bibliographic Details
Main Authors: Ahmed, QU (Author), Ching, SM (Author), Kadir, AA (Author), Omar, MH (Author), Rahim, MHA (Author), Sani, MHM (Author), Zakaria, ZA (Author)
Format: Article
Language:English
Published: 2019
Subjects:
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