The Effect of Wellsolve, a Novel Solubilizing Agent, on the Intestinal Barrier Function and Intestinal Absorption of Griseofulvin in Rats

The effect of Wellsolve, a new solubilizing agent, on the function of intestinal membrane harrier and transporters including P-glycoprotein (P-gp) and peptide transporter (PEPT1) was examined by an in vitro diffusion chamber and an in situ closed loop method. The model drugs used in this study were...

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Bibliographic Details
Main Authors: Gao, Y (Author), Hamid, KA (Author), Katsumi, H (Author), Lin, YL (Author), Sakane, T (Author), Yamamoto, A (Author)
Format: Article
Language:English
Series:BIOLOGICAL & PHARMACEUTICAL BULLETIN
Online Access:View Fulltext in Publisher