Rabbit as an Animal Model for Pharmacokinetics Studies of Enteric Capsule Contains Recombinant Human Keratinocyte Growth Factor Loaded Chitosan Nanoparticles

Rabbit as an Animal Model for Pharmacokinetics Studies of Enteric Capsule Contains Recombinant Human Keratinocyte Growth Factor Loaded Chitosan Nanoparticles

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Background: Recombinant human keratinocyte growth factor (rHuKGF) has gained considerable attention by researchers as epithelial cells proliferating agent. Moreover, intravenous truncated rHuKGF (palifermin) has been approved by Food and Drug Administration (FDA) to treat and prevent chemotherapy-in...

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Bibliographic Details
Main Authors: Cheah, SC (Author), Elumalai, M (Author), Kumar, PV (Author), Majeed, AB (Author), Maki, MAA (Author), Raghavan, B (Author), Tatt, LM (Author), Wei, YS (Author)
Format: Article
Language:English
Published: 2019
Subjects:
ABSORPTION
bioavailability
BIOAVAILABILITY
CELLS
CELLULAR UPTAKE
chitosan nanoparticles
DELIVERY
EXPRESSION
fluorescence imaging
MECHANISM
MTT COLORIMETRIC ASSAY
PALIFERMIN
PERMEABILITY
pharmacokinetics
proliferation
protein delivery
Recombinant human keratinocyte growth factor
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