Synthesis of novel 3,4-fused pyrazolidinone gamma-lactam bicyclic moieties from 2,3-dioxo-4-carboxy-5-(substituted)pyrrolidines
A new pathway for the synthesis of novel 3,4-fused pyrazolidinone gamma-lactam (4) starting from 2,3-dioxo-4-carboxy-5-(substituted)pyrrolidines (1) was developed. The key synthetic strategy involved hydrazonation of the precursor 1 followed by subsequent reduction reaction of the enamino ester 2 an...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |