BIOASSAY-GUIDED ISOLATION OF OCHROLIFUANINE: A BISINDOLE ALKALOID OF DYERA COSTULATA ACTIVE ON TRYPANOSOMA BRUCEI BRUCEI
Dyera costulata, locally known as jelutong, have shown promising in vitro inhibitory activity against Trypanosoma brucei brucei strain BS221. The methanolic leaf extract, evaluated using Alamar Blue Assay, showed strong antitrypanosomal activity (IC50 0.58 +/- 0.01 mu g mL(-1)) and high selectivity...
Main Authors: | Getha, K (Author), Lili-Sahira, H (Author), Mohd-Hafidz-Hadi, A (Author), Mohd-Ilham, A (Author), Muhd-Haffiz, J (Author), Muhd-Syamil, A (Author), Norhayati, I (Author), Nurhayati, ZA (Author) |
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Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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