Annatto (Bixa orellana) delta-TCT Supplementation Protection against Embryonic Malformations through Alterations in PI3K/Akt-Cyclin D1 Pathway

Annatto (Bixa orellana) delta-TCT Supplementation Protection against Embryonic Malformations through Alterations in PI3K/Akt-Cyclin D1 Pathway

Protective action by annatto-derived delta-tocotrienol (delta-TCT) and soy-derived alpha-tocopherol (alpha-TOC) through the regulation of the PI3K/Akt-cyclin D1 pathway against nicotine-induced DNA damage is the focus of the present study. Nicotine, which has been widely reported to have numerous ad...

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Bibliographic Details
Main Authors: Ab Rahim, S (Author), Khan, NAMN (Author), Mutalip, SSM (Author), Rajikin, MH (Author)
Format: Article
Language:English
Published: 2019
Subjects:
ALPHA-TOCOPHEROL
annatto delta-tocotrienol
ANTIOXIDANT PROPERTIES
BREAST-CANCER CELLS
CYCLIN-E
DEPENDENT REGULATION
GAMMA-TOCOTRIENOL
INDUCED APOPTOSIS
murine preimplantation embryos
nicotine
NICOTINE
reproductive toxicant
STEM-CELLS
tocopherols
vitamin E
VITAMIN-E
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