Inhalable Microparticles Embedding Calcium Phosphate Nanoparticles for Heart Targeting: The Formulation Experimental Design

Inhalable Microparticles Embedding Calcium Phosphate Nanoparticles for Heart Targeting: The Formulation Experimental Design

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Inhalation of Calcium Phosphate nanoparticles (CaPs) has recently unmasked the potential of this nanomedicine for a respiratory lung-to-heart drug delivery targeting the myocardial cells. In this work, we investigated the development of a novel highly respirable dry powder embedding crystalline CaPs...

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Bibliographic Details
Main Authors: Bettini, R (Author), Buttini, F (Author), Catalucci, D (Author), Colombo, G (Author), Colombo, P (Author), De Luca, C (Author), Degli Esposti, L (Author), Dotti, A (Author), Iafisco, M (Author), Quarta, E (Author), Rekkas, DM (Author), Rossi, A (Author), Sonvico, F (Author), Trevisi, G (Author), Wong, TW (Author)
Format: Article
Language:English
Published: 2021
Subjects:
calcium phosphate nanoparticles
design of experiment
INHALATION
MANNITOL
microparticles embedding nanoparticles
POWDER
PRODUCT
pulmonary delivery
QUALITY
SPRAY
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