Taurine protects against retinal and optic nerve damage induced by endothelin-1 in rats via antioxidant effects

Taurine protects against retinal and optic nerve damage induced by endothelin-1 in rats via antioxidant effects

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Endothelin-1 (ET-1), a potent vasoconstrictor, is involved in retinal vascular dysregulation and oxidative stress in glaucomatous eyes. Taurine (TAU), a naturally occurring free amino acid, is known for its neuroprotective and antioxidant properties. Hence, we evaluated its neuroprotective propertie...

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Bibliographic Details
Main Authors: Agarwal, P (Author), Agarwal, R (Author), Arfuzir, NNN (Author), Iezhitsa, I (Author), Ismail, NM (Author), Sidek, S (Author)
Format: Article
Language:English
Published: 2018
Subjects:
ANTERIOR
BRAIN
endothelin-1
FREE AMINO-ACIDS
GLAUCOMA
ISCHEMIA
MAGNESIUM ACETYLTAURATE
MECHANISMS
optic nerve
oxidative stress
POSTERIOR SEGMENT CHANGES
retina
taurine
VASOSPASM
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