Neuroprotective Potential of Mahanimbine against Lipopolysaccharides (LPS)-Induced Neuronal Deficits on SK-N-SH Cells and Antioxidant Potentials in ICR Mice Brain

Neuroprotective Potential of Mahanimbine against Lipopolysaccharides (LPS)-Induced Neuronal Deficits on SK-N-SH Cells and Antioxidant Potentials in ICR Mice Brain

Aims: Murraya koenigii commonly known as curry leaves, is traditionally used in India and other South Asian countries as a spice for its characteristic flavor and aroma. Mahanimbine is a major carbazole alkaloid derived from Murraya koenigii leaves. There are numerous reports that support the neurop...

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Bibliographic Details
Main Authors: Alhowail, A (Author), Azahan, NSM (Author), Lim, SM (Author), Majeed, AA (Author), Mani, V (Author), Ramasamy, K (Author), Sajid, S (Author)
Format: Article
Language:English
Published: 2019
Subjects:
antioxidant
BACE1
beta-secretase
BETA-SECRETASE
CARBAZOLE ALKALOIDS
EXTRACT
HYPOTHESIS
lipopolysaccharides
Mahanimbine
oxidative stress
OXIDATIVE STRESS
RESCUES MEMORY DEFICITS
SK-N-SH cells
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