Diastereoselective Reduction of 2,3-Dioxo-4-carboxy-5-substituted Pyrrolidines Using NaBH4/AcOH and Heterogenous Hydrogenation Reactions
Diastereoselective reduction of 2,3-dioxo-4-carboxy-5-(substituted) pyrrolidine 1 by NaBH4/AcOH and heterogenous hydrogenation were reported. Stereochemical assignment and diastereomeric ratios of the products were determined using H-1 NMR and single crystal X-ray analyses. The steric factors of the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2015
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |