Bioenergetic consequences of PINK1 mutations in Parkinson disease.

by Andrey Yurevich Abramov, Matthew Gegg, Anne Grunewald, Nicholas William Wood, Christine Klein, Anthony Henry Vernon Schapira
Published 2011-01-01

Discordance in monozygotic Parkinson's disease twins – continuum or dichotomy?

by Alexander Balck, Max Borsche, Meike Kasten, Katja Lohmann, Philip Seibler, Norbert Brüggemann, Christine Klein
Published 2019-06-01

The Role of Rare Coding Variants in Parkinson's Disease GWAS Loci

by Elisabeth Luisa Germer, Sophie Imhoff, Carles Vilariño-Güell, Meike Kasten, Philip Seibler, Norbert Brüggemann, International Parkinson’s Disease Genomics Consortium, Christine Klein, Joanne Trinh
Published 2019-12-01

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

by Christina M Lill, Johannes T Roehr, Matthew B McQueen, Fotini K Kavvoura, Sachin Bagade, Brit-Maren M Schjeide, Leif M Schjeide, Esther Meissner, Ute Zauft, Nicole C Allen, Tian Liu, Marcel Schilling, Kari J Anderson, Gary Beecham, Daniela Berg, Joanna M Biernacka, Alexis Brice, Anita L DeStefano, Chuong B Do, Nicholas Eriksson, Stewart A Factor, Matthew J Farrer, Tatiana Foroud, Thomas Gasser, Taye Hamza, John A Hardy, Peter Heutink, Erin M Hill-Burns, Christine Klein, Jeanne C Latourelle, Demetrius M Maraganore, Eden R Martin, Maria Martinez, Richard H Myers, Michael A Nalls, Nathan Pankratz, Haydeh Payami, Wataru Satake, William K Scott, Manu Sharma, Andrew B Singleton, Kari Stefansson, Tatsushi Toda, Joyce Y Tung, Jeffery Vance, Nick W Wood, Cyrus P Zabetian, 23andMe Genetic Epidemiology of Parkinson's Disease Consortium, International Parkinson's Disease Genomics Consortium, Parkinson's Disease GWAS Consortium, Wellcome Trust Case Control Consortium 2), Peter Young, Rudolph E Tanzi, Muin J Khoury, Frauke Zipp, Hans Lehrach, John P A Ioannidis, Lars Bertram
Published 2012-01-01

Bee venom and its component apamin as neuroprotective agents in a Parkinson disease mouse model.

by Daniel Alvarez-Fischer, Carmen Noelker, Franca Vulinović, Anne Grünewald, Caroline Chevarin, Christine Klein, Wolfgang H Oertel, Etienne C Hirsch, Patrick P Michel, Andreas Hartmann
Published 2013-01-01

The Importance of <i>Drosophila melanogaster</i> Research to UnCover Cellular Pathways Underlying Parkinson’s Disease

by Melissa Vos, Christine Klein
Published 2021-03-01

Frequency of Heterozygous Parkin (PRKN) Variants and Penetrance of Parkinson's Disease Risk Markers in the Population-Based CHRIS Cohort

by Maria Paulina Castelo Rueda, Athina Raftopoulou, Athina Raftopoulou, Martin Gögele, Max Borsche, David Emmert, Christian Fuchsberger, Essi M. Hantikainen, Vladimir Vukovic, Vladimir Vukovic, Christine Klein, Peter P. Pramstaller, Peter P. Pramstaller, Irene Pichler, Andrew A. Hicks
Published 2021-08-01

LIPAD (LRRK2/Luebeck International Parkinson's Disease) Study Protocol: Deep Phenotyping of an International Genetic Cohort

by Tatiana Usnich, Eva-Juliane Vollstedt, Nathalie Schell, Volha Skrahina, Xenia Bogdanovic, Hanaa Gaber, Toni M. Förster, Andreas Heuer, Natalia Koleva-Alazeh, Ilona Csoti, Ayse Nazli Basak, Sibel Ertan, Gencer Genc, Peter Bauer, Katja Lohmann, Anne Grünewald, Emma L. Schymanski, Joanne Trinh, Susen Schaake, Daniela Berg, Doreen Gruber, Stuart H. Isaacson, Andrea A. Kühn, Brit Mollenhauer, David J. Pedrosa, Kathrin Reetz, Esther M. Sammler, Enza Maria Valente, Franco Valzania, Jens Volkmann, Simone Zittel, Norbert Brüggemann, Norbert Brüggemann, Meike Kasten, Meike Kasten, Arndt Rolfs, Christine Klein, The LIPAD Study Group
Published 2021-08-01

Generation and characterization of human-derived iPSC lines from three pairs of monozygotic twins discordant for Parkinson's disease

by Marija Dulovic-Mahlow, Agnieszka Lukomska, Sokhna Haissatou Diaw, Alexander Balck, Max Borsche, Karen Grütz, Insa Lenz, Franziska Rudolph, Katja Lohmann, Christine Klein, Philip Seibler
Published 2019-12-01

Nanopore Single-Molecule Sequencing for Mitochondrial DNA Methylation Analysis: Investigating Parkin-Associated Parkinsonism as a Proof of Concept

by Theresa Lüth, Kobi Wasner, Christine Klein, Susen Schaake, Ronnie Tse, Sandro L. Pereira, Joshua Laß, Lasse Sinkkonen, Anne Grünewald, Anne Grünewald, Joanne Trinh
Published 2021-09-01

An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2

by Natalie Connor-Robson, Heather Booth, Jeffrey G. Martin, Benbo Gao, Kejie Li, Natalie Doig, Jane Vowles, Cathy Browne, Laura Klinger, Peter Juhasz, Christine Klein, Sally A. Cowley, Paul Bolam, Warren Hirst, Richard Wade-Martins
Published 2019-07-01

Qualitative Characteristics of Depression in Parkinson’s Patients and Controls

by Cleo Kritzinger, Eva-Juliane Vollstedt, Katja Hückelheim, Anne Lorwin, Julia Graf, Sinem Tunc, Christine Klein, Meike Kasten
Published 2015-01-01

Genome-Edited, TH-expressing Neuroblastoma Cells as a Disease Model for Dopamine-Related Disorders: A Proof-of-Concept Study on DJ-1-deficient Parkinsonism

by Jannik Prasuhn, Christoph U. Mårtensson, Victor Krajka, Christine Klein, Aleksandar Rakovic
Published 2018-01-01

Structural imaging in the presymptomatic stage of genetically determined parkinsonism

by Kathrin Reetz, Vera Tadic, Meike Kasten, Norbert Brüggemann, Alexander Schmidt, Johann Hagenah, Peter P. Pramstaller, Alfredo Ramirez, Maria I. Behrens, Hartwig R. Siebner, Christine Klein, Ferdinand Binkofski
Published 2010-09-01

Parkin Interacts with Apoptosis-Inducing Factor and Interferes with Its Translocation to the Nucleus in Neuronal Cells

by Marianna Guida, Alessandra Zanon, Luigi Montibeller, Alexandros A. Lavdas, Judith Ladurner, Francesca Pischedda, Aleksandar Rakovic, Francisco S. Domingues, Giovanni Piccoli, Christine Klein, Peter P. Pramstaller, Andrew A. Hicks, Irene Pichler
Published 2019-02-01

An omics-based strategy using coenzyme Q10 in patients with Parkinson’s disease: concept evaluation...

by Jannik Prasuhn, Norbert Brüggemann, Nicole Hessler, Daniela Berg, Thomas Gasser, Kathrin Brockmann, Denise Olbrich, Andreas Ziegler, Inke R. König, Christine Klein, Meike Kasten
Published 2019-08-01

The Use of Vitamin K2 in Patients With Parkinson's Disease and Mitochondrial Dysfunction (PD-K2): A...

by Jannik Prasuhn, Jannik Prasuhn, Meike Kasten, Meike Kasten, Melissa Vos, Inke R. König, Sebastian M. Schmid, Sebastian M. Schmid, Britta Wilms, Britta Wilms, Christine Klein, Norbert Brüggemann, Norbert Brüggemann
Published 2021-01-01

Increased insula-putamen connectivity in X-linked dystonia-parkinsonism

by Anne J. Blood, Jeff L. Waugh, Thomas F. Münte, Marcus Heldmann, Aloysius Domingo, Christine Klein, Hans C. Breiter, Lillian V. Lee, Raymond L. Rosales, Norbert Brüggemann
Published 2018-01-01

Mitochondrial Mechanisms of LRRK2 G2019S Penetrance

by Sylvie Delcambre, Jenny Ghelfi, Nassima Ouzren, Léa Grandmougin, Catherine Delbrouck, Catherine Delbrouck, Philip Seibler, Kobi Wasner, Jan O. Aasly, Christine Klein, Joanne Trinh, Sandro L. Pereira, Anne Grünewald, Anne Grünewald
Published 2020-08-01

Assessment of Olfactory Function in MAPT-Associated Neurodegenerative Disease Reveals Odor...

by Katerina Markopoulou, Bruce A Chase, Piotr Robowski, Audrey Strongosky, Ewa Narożańska, Emilia J Sitek, Mariusz Berdynski, Maria Barcikowska, Matt C Baker, Rosa Rademakers, Jarosław Sławek, Christine Klein, Katja Hückelheim, Meike Kasten, Zbigniew K Wszolek
Published 2016-01-01