A large study reveals no association between APOE and Parkinson's disease

by Monica Federoff, Belen Jimenez-Rolando, Michael A. Nalls, Andrew B. Singleton
Published 2012-05-01

Genome wide assessment of young onset Parkinson's disease from Finland.

by Dena G Hernandez, Michael A Nalls, Pauli Ylikotila, Margaux Keller, John A Hardy, Kari Majamaa, Andrew B Singleton
Published 2012-01-01

Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis.

by James F Meschia, Andrew Singleton, Michael A Nalls, Stephen S Rich, Pankaj Sharma, Luigi Ferrucci, Mar Matarin, Dena G Hernandez, Kerra Pearce, Thomas G Brott, Robert D Brown, John Hardy, Bradford B Worrall
Published 2011-01-01

Measures of autozygosity in decline: globalization, urbanization, and its implications for medical genetics.

by Michael A Nalls, Javier Simon-Sanchez, J Raphael Gibbs, Coro Paisan-Ruiz, Jose Tomas Bras, Toshiko Tanaka, Mar Matarin, Sonja Scholz, Charles Weitz, Tamara B Harris, Luigi Ferrucci, John Hardy, Andrew B Singleton
Published 2009-03-01

Plasma 24-metabolite panel predicts preclinical transition to clinical stages of Alzheimer’s disease

by Massimo S Fiandaca, Xioagang eZhong, Amrita K Cheema, Michael H. Orquiza, Swathi eChidambaram, Ming T Tan, Carole Roan Gresenz, Kevin T FitzGerald, Michael A Nalls, Andrew B Singleton, Mark eMapstone, Howard J Federoff
Published 2015-11-01

Genetic variability in CLU and its association with Alzheimer's disease.

by Rita J Guerreiro, John Beck, J Raphael Gibbs, Isabel Santana, Martin N Rossor, Jonathan M Schott, Michael A Nalls, Helena Ribeiro, Beatriz Santiago, Nick C Fox, Catarina Oliveira, John Collinge, Simon Mead, Andrew Singleton, John Hardy
Published 2010-03-01

Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits

by Mateus H. Gouveia, Amy R. Bentley, Hampton Leonard, Karlijn A. C. Meeks, Kenneth Ekoru, Guanjie Chen, Michael A. Nalls, Eleanor M. Simonsick, Eduardo Tarazona-Santos, Maria Fernanda Lima-Costa, Adebowale Adeyemo, Daniel Shriner, Charles N. Rotimi
Published 2021-02-01

Using genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degeneration.

by Kylee L Spencer, Lana M Olson, Nathalie Schnetz-Boutaud, Paul Gallins, Anita Agarwal, Alessandro Iannaccone, Stephen B Kritchevsky, Melissa Garcia, Michael A Nalls, Anne B Newman, William K Scott, Margaret A Pericak-Vance, Jonathan L Haines
Published 2011-03-01

NOTCH3 variants and risk of ischemic stroke.

by Owen A Ross, Alexandra I Soto-Ortolaza, Michael G Heckman, Christophe Verbeeck, Daniel J Serie, Sruti Rayaprolu, Stephen S Rich, Michael A Nalls, Andrew Singleton, Rita Guerreiro, Emma Kinsella, Zbigniew K Wszolek, Thomas G Brott, Robert D Brown, Bradford B Worrall, James F Meschia
Published 2013-01-01

Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based i...

by Andrew R Wood, John R B Perry, Toshiko Tanaka, Dena G Hernandez, Hou-Feng Zheng, David Melzer, J Raphael Gibbs, Michael A Nalls, Michael N Weedon, Tim D Spector, J Brent Richards, Stefania Bandinelli, Luigi Ferrucci, Andrew B Singleton, Timothy M Frayling
Published 2013-01-01

Cooperative genome-wide analysis shows increased homozygosity in early onset Parkinson's disease.

by Javier Simón-Sánchez, Laura L Kilarski, Michael A Nalls, Maria Martinez, Claudia Schulte, Peter Holmans, International Parkinson's Disease Genomics Consortium, Wellcome Trust Case Control Consortium, Thomas Gasser, John Hardy, Andrew B Singleton, Nicholas W Wood, Alexis Brice, Peter Heutink, Nigel Williams, Huw R Morris
Published 2012-01-01

Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain.

by J Raphael Gibbs, Marcel P van der Brug, Dena G Hernandez, Bryan J Traynor, Michael A Nalls, Shiao-Lin Lai, Sampath Arepalli, Allissa Dillman, Ian P Rafferty, Juan Troncoso, Robert Johnson, H Ronald Zielke, Luigi Ferrucci, Dan L Longo, Mark R Cookson, Andrew B Singleton
Published 2010-05-01

A network-based approach to prioritize results from genome-wide association studies.

by Nirmala Akula, Ancha Baranova, Donald Seto, Jeffrey Solka, Michael A Nalls, Andrew Singleton, Luigi Ferrucci, Toshiko Tanaka, Stefania Bandinelli, Yoon Shin Cho, Young Jin Kim, Jong-Young Lee, Bok-Ghee Han, Bipolar Disorder Genome Study (BiGS) Consortium, Wellcome Trust Case-Control Consortium, Francis J McMahon
Published 2011-01-01

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.

by Celeste Sassi, Perry G Ridge, Michael A Nalls, Raphael Gibbs, Jinhui Ding, Michelle K Lupton, Claire Troakes, Katie Lunnon, Safa Al-Sarraj, Kristelle S Brown, Christopher Medway, Jenny Lord, James Turton, ARUK Consortium, Kevin Morgan, John F Powell, John S Kauwe, Carlos Cruchaga, Jose Bras, Alison M Goate, Andrew B Singleton, Rita Guerreiro, John Hardy
Published 2016-01-01

A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.

by Rehan Qayyum, Beverly M Snively, Elad Ziv, Michael A Nalls, Yongmei Liu, Weihong Tang, Lisa R Yanek, Leslie Lange, Michele K Evans, Santhi Ganesh, Melissa A Austin, Guillaume Lettre, Diane M Becker, Alan B Zonderman, Andrew B Singleton, Tamara B Harris, Emile R Mohler, Benjamin A Logsdon, Charles Kooperberg, Aaron R Folsom, James G Wilson, Lewis C Becker, Alexander P Reiner
Published 2012-01-01

Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene.

by David Reich, Michael A Nalls, W H Linda Kao, Ermeg L Akylbekova, Arti Tandon, Nick Patterson, James Mullikin, Wen-Chi Hsueh, Ching-Yu Cheng, Josef Coresh, Eric Boerwinkle, Man Li, Alicja Waliszewska, Julie Neubauer, Rongling Li, Tennille S Leak, Lynette Ekunwe, Joe C Files, Cheryl L Hardy, Joseph M Zmuda, Herman A Taylor, Elad Ziv, Tamara B Harris, James G Wilson
Published 2009-01-01

Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus.

by Daniah Trabzuni, Mina Ryten, Warren Emmett, Adaikalavan Ramasamy, Karl J Lackner, Tanja Zeller, Robert Walker, Colin Smith, Patrick A Lewis, Adamantios Mamais, Rohan de Silva, Jana Vandrovcova, International Parkinson Disease Genomics Consortium (IPDGC), Dena Hernandez, Michael A Nalls, Manu Sharma, Sophie Garnier, Suzanne Lesage, Javier Simon-Sanchez, Thomas Gasser, Peter Heutink, Alexis Brice, Andrew Singleton, Huaibin Cai, Eric Schadt, Nicholas W Wood, Rina Bandopadhyay, Michael E Weale, John Hardy, Vincent Plagnol
Published 2013-01-01

Genome-wide association studies of the PR interval in African Americans.

by J Gustav Smith, Jared W Magnani, Cameron Palmer, Yan A Meng, Elsayed Z Soliman, Solomon K Musani, Kathleen F Kerr, Renate B Schnabel, Steven A Lubitz, Nona Sotoodehnia, Susan Redline, Arne Pfeufer, Martina Müller, Daniel S Evans, Michael A Nalls, Yongmei Liu, Anne B Newman, Alan B Zonderman, Michele K Evans, Rajat Deo, Patrick T Ellinor, Dina N Paltoo, Christopher Newton-Cheh, Emelia J Benjamin, Reena Mehra, Alvaro Alonso, Susan R Heckbert, Ervin R Fox, Candidate-gene Association Resource (CARe) Consortium
Published 2011-02-01

Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.

by Yukinori Okada, Tomomitsu Hirota, Yoichiro Kamatani, Atsushi Takahashi, Hiroko Ohmiya, Natsuhiko Kumasaka, Koichiro Higasa, Yumi Yamaguchi-Kabata, Naoya Hosono, Michael A Nalls, Ming Huei Chen, Frank J A van Rooij, Albert V Smith, Toshiko Tanaka, David J Couper, Neil A Zakai, Luigi Ferrucci, Dan L Longo, Dena G Hernandez, Jacqueline C M Witteman, Tamara B Harris, Christopher J O'Donnell, Santhi K Ganesh, Koichi Matsuda, Tatsuhiko Tsunoda, Toshihiro Tanaka, Michiaki Kubo, Yusuke Nakamura, Mayumi Tamari, Kazuhiko Yamamoto, Naoyuki Kamatani
Published 2011-06-01

Human Obesity Associated with an Intronic SNP in the Brain-Derived Neurotrophic Factor Locus

by Zongyang Mou, Thomas M. Hyde, Barbara K. Lipska, Keri Martinowich, Peter Wei, Chiew-Jen Ong, Lindsay A. Hunter, Gladys I. Palaguachi, Eva Morgun, Rujia Teng, Chen Lai, Tania A. Condarco, Andrew P. Demidowich, Amanda J. Krause, Leslie J. Marshall, Karin Haack, V. Saroja Voruganti, Shelley A. Cole, Nancy F. Butte, Anthony G. Comuzzie, Michael A. Nalls, Alan B. Zonderman, Andrew B. Singleton, Michele K. Evans, Bronwen Martin, Stuart Maudsley, Jack W. Tsao, Joel E. Kleinman, Jack A. Yanovski, Joan C. Han
Published 2015-11-01