Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice.

by Tohru Matsuki, Mariam Zaka, Rita Guerreiro, Marcel P van der Brug, Jonathan A Cooper, Mark R Cookson, John A Hardy, Brian W Howell
Published 2012-01-01

Alzheimer’s Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation

by Karpagam Srinivasan, Brad A. Friedman, Ainhoa Etxeberria, Melanie A. Huntley, Marcel P. van der Brug, Oded Foreman, Jonathan S. Paw, Zora Modrusan, Thomas G. Beach, Geidy E. Serrano, David V. Hansen
Published 2020-06-01

Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses

by Karpagam Srinivasan, Brad A. Friedman, Jessica L. Larson, Benjamin E. Lauffer, Leonard D. Goldstein, Laurie L. Appling, Jovencio Borneo, Chungkee Poon, Terence Ho, Fang Cai, Pascal Steiner, Marcel P. van der Brug, Zora Modrusan, Joshua S. Kaminker, David V. Hansen
Published 2016-04-01

Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models

by Brad A. Friedman, Karpagam Srinivasan, Gai Ayalon, William J. Meilandt, Han Lin, Melanie A. Huntley, Yi Cao, Seung-Hye Lee, Patrick C.G. Haddick, Hai Ngu, Zora Modrusan, Jessica L. Larson, Joshua S. Kaminker, Marcel P. van der Brug, David V. Hansen
Published 2018-01-01

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

by Elisa Greggio, Shushant Jain, Ann Kingsbury, Rina Bandopadhyay, Patrick Lewis, Alice Kaganovich, Marcel P. van der Brug, Alexandra Beilina, Jeff Blackinton, Kelly Jean Thomas, Rili Ahmad, David W. Miller, Sashi Kesavapany, Andrew Singleton, Andrew Lees, Robert J. Harvey, Kirsten Harvey, Mark R. Cookson
Published 2006-08-01

Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain.

by J Raphael Gibbs, Marcel P van der Brug, Dena G Hernandez, Bryan J Traynor, Michael A Nalls, Shiao-Lin Lai, Sampath Arepalli, Allissa Dillman, Ian P Rafferty, Juan Troncoso, Robert Johnson, H Ronald Zielke, Luigi Ferrucci, Dan L Longo, Mark R Cookson, Andrew B Singleton
Published 2010-05-01

Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue

by Michael J. Devine, Alice Kaganovich, Mina Ryten, Adamantios Mamais, Daniah Trabzuni, Claudia Manzoni, Philip McGoldrick, Diane Chan, Allissa Dillman, Julia Zerle, Susannah Horan, Jan-Willem Taanman, John Hardy, Jose-Felix Marti-Masso, Daniel Healy, Anthony H. Schapira, Benjamin Wolozin, Rina Bandopadhyay, Mark R. Cookson, Marcel P. van der Brug, Patrick A. Lewis
Published 2012-01-01

Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue.

by Michael J. Devine, Alice Kaganovich, Mina Ryten, Adamantios Mamais, Daniah Trabzuni, Claudia Manzoni, Philip McGoldrick, Diane Chan, Allissa Dillman, Julia Zerle, Susannah Horan, Jan-Willem Taanman, John Hardy, Jose-Felix Marti-Masso, Daniel Healy, Anthony H. Schapira, Benjamin Wolozin, Rina Bandopadhyay, Mark R. Cookson, Marcel P. van der Brug, Patrick A. Lewis
Published 2012-01-01

Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue.

by Michael J Devine, Alice Kaganovich, Mina Ryten, Adamantios Mamais, Daniah Trabzuni, Claudia Manzoni, Philip McGoldrick, Diane Chan, Allissa Dillman, Julia Zerle, Susannah Horan, Jan-Willem Taanman, John Hardy, Jose-Felix Marti-Masso, Daniel Healy, Anthony H Schapira, Benjamin Wolozin, Rina Bandopadhyay, Mark R Cookson, Marcel P van der Brug, Patrick A Lewis
Published 2011-01-01