LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same

by Daniel C. Berwick, George R. Heaton, Sonia Azeggagh, Kirsten Harvey
Published 2019-12-01

Extent of white matter lesion is associated with early hemorrhagic transformation in acute ischemic stroke related to atrial fibrillation

by Lucio D'Anna, Filippos T. Filippidis, Kirsten Harvey, Marilena Marinescu, Paul Bentley, Eleni Korompoki, Roland Veltkamp
Published 2021-08-01

A critical role for glycine transporters in hyperexcitability disorders

by Robert J Harvey, Eloisa Carta, Brian R Pearce, Seo-Kyung Chung, Stéphane Supplisson, Mark I Rees, Mark I Rees, Kirsten Harvey
Published 2008-03-01

Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis

by George R. Heaton, Natalie Landeck, Adamantios Mamais, Mike A. Nalls, Jonathon Nixon-Abell, Ravindran Kumaran, Alexandra Beilina, Laura Pellegrini, Yan Li, Kirsten Harvey, Mark R. Cookson
Published 2020-07-01

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition

by Rina Bandopadhyay, Ann E. Kingsbury, Miratul M. Muqit, Kirsten Harvey, Andrew R. Reid, Linda Kilford, Simone Engelender, Michael G. Schlossmacher, Nicholas W. Wood, David S. Latchman, Robert J. Harvey, Andrew J. Lees
Published 2005-11-01

Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability

by Tzu-Ting Chiou, Philip Long, Alexandra Schumann-Gillett, Venkateswarlu Kanamarlapudi, Stefan A. Haas, Kirsten Harvey, Megan L. O’Mara, Angel L. De Blas, Vera M. Kalscheuer, Robert J. Harvey, Robert J. Harvey
Published 2019-03-01

Distinct Mechanisms of Pathogenic DJ-1 Mutations in Mitochondrial Quality Control

by Daniela Strobbe, Daniela Strobbe, Alexis A. Robinson, Kirsten Harvey, Lara Rossi, Caterina Ferraina, Caterina Ferraina, Valerio de Biase, Carlo Rodolfo, Robert J. Harvey, Robert J. Harvey, Michelangelo Campanella, Michelangelo Campanella, Michelangelo Campanella
Published 2018-03-01

The glycinergic system in human startle disease: a genetic screening approach

by Jeff S Davies, Seo-Kyung Chung, Rhys H Thomas, Angela Robinson, Carrie L Hammond, Jonathan G L Mullins, Eloisa Carta, Brian R Pearce, Kirsten Harvey, Robert J Harvey, Mark I Rees, Mark I Rees
Published 2010-03-01

Novel Missense Mutation A789V in IQSEC2 Underlies X-Linked Intellectual Disability in the MRX78 Family

by Vera M. Kalscheuer, Vera M. Kalscheuer, Victoria M. James, Miranda L. Himelright, Philip Long, Renske Oegema, Corinna Jensen, Melanie Bienek, Hao Hu, Stefan A. Haas, Maya Topf, A. Jeannette M. Hoogeboom, Kirsten Harvey, Randall Walikonis, Robert J. Harvey
Published 2016-01-01

Novel missense mutations in the glycine receptor β subunit gene (GLRB) in startle disease

by Victoria M. James, Anna Bode, Seo-Kyung Chung, Jennifer L. Gill, Maartje Nielsen, Frances M. Cowan, Mihailo Vujic, Rhys H. Thomas, Mark I. Rees, Kirsten Harvey, Angelo Keramidas, Maya Topf, Ieke Ginjaar, Joseph W. Lynch, Robert J. Harvey
Published 2013-04-01

The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network

by Alexandra Beilina, Luis Bonet-Ponce, Ravindran Kumaran, Jennifer J. Kordich, Morié Ishida, Adamantios Mamais, Alice Kaganovich, Sara Saez-Atienzar, David C. Gershlick, Dorien A. Roosen, Laura Pellegrini, Vlad Malkov, Matthew J. Fell, Kirsten Harvey, Juan S. Bonifacino, Darren J. Moore, Mark R. Cookson
Published 2020-05-01

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

by Elisa Greggio, Shushant Jain, Ann Kingsbury, Rina Bandopadhyay, Patrick Lewis, Alice Kaganovich, Marcel P. van der Brug, Alexandra Beilina, Jeff Blackinton, Kelly Jean Thomas, Rili Ahmad, David W. Miller, Sashi Kesavapany, Andrew Singleton, Andrew Lees, Robert J. Harvey, Kirsten Harvey, Mark R. Cookson
Published 2006-08-01