Negative regulation of autophagy by UBA6-BIRC6–mediated ubiquitination of LC3

by Rui Jia, Juan S Bonifacino
Published 2019-11-01

How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4

by Xuefeng Ren, Sang Yoon Park, Juan S Bonifacino, James H Hurley
Published 2014-01-01

Co-assembly of viral envelope glycoproteins regulates their polarized sorting in neurons.

by Rafael Mattera, Ginny G Farías, Gonzalo A Mardones, Juan S Bonifacino
Published 2014-05-01

Mechanisms of Polarized Organelle Distribution in Neurons

by Dylan J. Britt, Ginny G. Farías, Carlos M. Guardia, Juan S. Bonifacino
Published 2016-03-01

Sorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone

by Ginny G. Farías, Carlos M. Guardia, Dylan J. Britt, Xiaoli Guo, Juan S. Bonifacino
Published 2015-11-01

Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps.

by Javier G Magadán, F Javier Pérez-Victoria, Rachid Sougrat, Yihong Ye, Klaus Strebel, Juan S Bonifacino
Published 2010-04-01

The autophagy protein ATG9A promotes HIV-1 infectivity

by Elodie Mailler, Abdul A. Waheed, Sang-Yoon Park, David C. Gershlick, Eric O. Freed, Juan S. Bonifacino
Published 2019-07-01

Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning.

by Carlos M Guardia, Raffaella De Pace, Aritra Sen, Amra Saric, Michal Jarnik, David A Kolin, Ambarish Kunwar, Juan S Bonifacino
Published 2019-05-01

Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons

by Raffaella De Pace, Dylan J. Britt, Jeffrey Mercurio, Arianne M. Foster, Lucas Djavaherian, Victoria Hoffmann, Daniel Abebe, Juan S. Bonifacino
Published 2020-06-01

SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum

by Amra Saric, Spencer A. Freeman, Chad D. Williamson, Michal Jarnik, Carlos M. Guardia, Michael S. Fernandopulle, David C. Gershlick, Juan S. Bonifacino
Published 2021-07-01

α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes.

by Aysegul Dilsizoglu Senol, Maura Samarani, Sylvie Syan, Carlos M Guardia, Takashi Nonaka, Nalan Liv, Patricia Latour-Lambert, Masato Hasegawa, Judith Klumperman, Juan S Bonifacino, Chiara Zurzolo
Published 2021-07-01

Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration.

by Passley Hargrove-Grimes, Anupam K Mondal, Jessica Gumerson, Jacob Nellissery, Angel M Aponte, Linn Gieser, Haohua Qian, Robert N Fariss, Juan S Bonifacino, Tiansen Li, Anand Swaroop
Published 2020-12-01

Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery

by Carlos M. Guardia, Xiao-Feng Tan, Tengfei Lian, Mitra S. Rana, Wenchang Zhou, Eric T. Christenson, Augustus J. Lowry, José D. Faraldo-Gómez, Juan S. Bonifacino, Jiansen Jiang, Anirban Banerjee
Published 2020-06-01

A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1

by Anika V. Prabhu, Insung Kang, Raffaella De Pace, Christopher A. Wassif, Hideji Fujiwara, Pamela Kell, Xuntian Jiang, Daniel S. Ory, Juan S. Bonifacino, Michael E. Ward, Forbes D. Porter
Published 2021-10-01

Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome.

by Raffaella De Pace, Miguel Skirzewski, Markus Damme, Rafael Mattera, Jeffrey Mercurio, Arianne M Foster, Loreto Cuitino, Michal Jarnik, Victoria Hoffmann, H Douglas Morris, Tae-Un Han, Grazia M S Mancini, Andrés Buonanno, Juan S Bonifacino
Published 2018-04-01

The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network

by Alexandra Beilina, Luis Bonet-Ponce, Ravindran Kumaran, Jennifer J. Kordich, Morié Ishida, Adamantios Mamais, Alice Kaganovich, Sara Saez-Atienzar, David C. Gershlick, Dorien A. Roosen, Laura Pellegrini, Vlad Malkov, Matthew J. Fell, Kirsten Harvey, Juan S. Bonifacino, Darren J. Moore, Mark R. Cookson
Published 2020-05-01