Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors

by Suleyman Akocak, Nabih Lolak, Silvia Bua, Claudiu T. Supuran
Published 2018-01-01

Fluoroenesulphonamides: N-sulphonylurea isosteres showing nanomolar selective cancer-related transmembrane human carbonic anhydrase inhibition

by Benoit Métayer, Andrea Angeli, Agnès Mingot, Kévin Jouvin, Gwilherm Evano, Claudiu T. Supuran, Sébastien Thibaudeau
Published 2018-01-01

CAIX furthers tumour progression in the hypoxic tumour microenvironment of esophageal carcinoma and is a possible therapeutic target

by Astrid Drenckhan, Morton Freytag, Claudiu T. Supuran, Guido Sauter, Jakob R. Izbicki, Stephanie J. Gros
Published 2018-01-01

Inhibition of α-, β-, γ-, and δ-carbonic anhydrases from bacteria and diatoms with N′-aryl-N-hydroxy-ureas

by Emanuela Berrino, Murat Bozdag, Sonia Del Prete, Fatmah A. S. Alasmary, Linah S. Alqahtani, Zeid AlOthman, Clemente Capasso, Claudiu T. Supuran
Published 2018-01-01

Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action

by Marco Bragagni, Fabrizio Carta, Sameh M. Osman, Zeid AlOthman, Claudiu T. Supuran
Published 2017-01-01

Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii

by Silvia Bua, Murat Bozdag, Sonia Del Prete, Fabrizio Carta, William A. Donald, Clemente Capasso, Claudiu T. Supuran
Published 2018-01-01

Phaeodactylum tricornutum as a model organism for testing the membrane penetrability of sulphonamide carbonic anhydrase inhibitors

by Alessandra Rogato, Sonia Del Prete, Alessio Nocentini, Vincenzo Carginale, Claudiu T. Supuran, Clemente Capasso
Published 2019-01-01

Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative

by David Bibi, Bella Shusterman, Alessio Nocentini, Claudiu T. Supuran, Meir Bialer
Published 2019-01-01

Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach

by Giuseppina De Simone, Anna Di Fiore, Emanuela Truppo, Emma Langella, Daniela Vullo, Claudiu T. Supuran, Simona Maria Monti
Published 2019-01-01

The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy

by Elena Andreucci, Jessica Ruzzolini, Silvia Peppicelli, Francesca Bianchini, Anna Laurenzana, Fabrizio Carta, Claudiu T. Supuran, Lido Calorini
Published 2019-01-01

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies

by Ciro Milite, Giorgio Amendola, Alessio Nocentini, Silvia Bua, Alessandra Cipriano, Elisabetta Barresi, Alessandra Feoli, Ettore Novellino, Federico Da Settimo, Claudiu T. Supuran, Sabrina Castellano, Sandro Cosconati, Sabrina Taliani
Published 2019-01-01

Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles

by Alessio Nocentini, Roberta Cadoni, Pascal Dumy, Claudiu T. Supuran, Jean-Yves Winum
Published 2018-01-01

Sulfonamide inhibition studies of two β-carbonic anhydrases from the ascomycete fungus Sordaria macrospora, CAS1 and CAS2

by Daniela Vullo, Ronny Lehneck, Stefanie Pöggeler, Claudiu T. Supuran
Published 2018-01-01

Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms

by Melissa D’Ascenzio, Paolo Guglielmi, Simone Carradori, Daniela Secci, Rosalba Florio, Adriano Mollica, Mariangela Ceruso, Atilla Akdemir, Anatoly P. Sobolev, Claudiu T. Supuran
Published 2017-01-01

Carbonic anhydrase inhibitory properties of some uracil derivatives

by Emir Alper Türkoğlu, Murat Şentürk, Claudiu T. Supuran, Deniz Ekinci
Published 2017-01-01

Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors

by Claudia Melis, Rita Meleddu, Andrea Angeli, Simona Distinto, Giulia Bianco, Clemente Capasso, Filippo Cottiglia, Rossella Angius, Claudiu T. Supuran, Elias Maccioni
Published 2017-01-01

Dioxygen, an unexpected carbonic anhydrase ligand

by Marta Ferraroni, Roberto Gaspari, Andrea Scozzafava, Andrea Cavalli, Claudiu T. Supuran
Published 2018-01-01

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes

by Silvia Bua, Emanuela Berrino, Sonia Del Prete, Vallabhaneni S. Murthy, Vijayaparthasarathi Vijayakumar, Yasinalli Tamboli, Clemente Capasso, Elisabetta Cerbai, Alessandro Mugelli, Fabrizio Carta, Claudiu T. Supuran
Published 2018-01-01

Design, synthesis and evaluation of 18F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging

by Zhengxing Zhang, Joseph Lau, Chengcheng Zhang, Nadine Colpo, Alessio Nocentini, Claudiu T. Supuran, François Bénard, Kuo-Shyan Lin
Published 2017-01-01

Quantitative assessment of specific carbonic anhydrase inhibitors effect on hypoxic cells using electrical impedance assays

by Luciana Stanica, Mihaela Gheorghiu, Miruna Stan, Cristina Polonschii, Sorin David, Dumitru Bratu, Anca Dinischiotu, Claudiu T. Supuran, Eugen Gheorghiu
Published 2017-01-01