Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues

by Zhang, Liguo, Richards, Alexsia, Barrasa, M. Inmaculada, Hughes, Stephen H., Young, Richard A., Jaenisch, Rudolf
Published 2021

CD8[superscript +] T Cells from Mice Transnuclear for a TCR that Recognizes a Single H-2K[superscript b]-Restricted MHV68 Epitope Derived from gB-ORF8 Help Control Infection

by Sehrawat, Sharvan, Kirak, Oktay, Koenig, Paul-Albert, Isaacson, Marisa K., Marques, Sofia, Bozkurt, Gunes, Simas, J. Pedro, Jaenisch, Rudolf, Ploegh, Hidde
Published 2014

Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype

by Omer Javed, Attya, Muffat, Julien, Su, Kuan-Chung, Lungjangwa, Tenzin, Aubourg, Patrick, Li, Yun, Cohen, Malkiel A, Cheeseman, Iain M, Jaenisch, Rudolf
Published 2018

Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice

by Zhao, Zhigang, Chen, Li, Dawlaty, Meelad M, Pan, Feng, Weeks, Ophelia, Zhou, Yuan, Cao, Zeng, Shi, Hui, Wang, Jiapeng, Lin, Li, Chen, Shi, Yuan, Weiping, Qin, Zhaohui, Ni, Hongyu, Nimer, Stephen D, Yang, Feng-Chun, Jaenisch, Rudolf, Jin, Peng, Xu, Mingjiang
Published 2016

Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions

by Ji, Xiong, Abraham, Brian J., Lee, Tong Ihn, Jaenisch, Rudolf, Bradner, James E., Young, Richard A., Dadon, Daniel Benjamin
Published 2015

Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene

by Liu, X. Shawn, Wu, Hao, Krzisch, Marine, Wu, Xuebing, Graef, John, Muffat, Julien, Hnisz, Denes, Li, Charles Han, Yuan, Bingbing, Xu, Chuanyun, Li, Yun, Vershkov, Dan, Cacace, Angela, Young, Richard A., Jaenisch, Rudolf
Published 2020

Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development

by Dawlaty, Meelad M, Breiling, Achim, Le, Thuc, Raddatz, Günter, Barrasa, M. Inmaculada, Cheng, Albert W, Gao, Qing, Powell, Benjamin E, Li, Zhe, Xu, Mingjiang, Faull, Kym F, Lyko, Frank, Jaenisch, Rudolf
Published 2017

SMARCE1 is required for the invasive progression of in situ cancers

by Feng, Yu-Xiong, Tizabi, Minu D., Cohen, Malkiel A., Sanduja, Sandhya, Reinhardt, Ferenc, Pandey, Jai, Sokol, Ethan Samuel, Jin, Dexter X., Miller, Daniel Handel, Superville, Daphne A., Jaenisch, Rudolf, Gupta, Piyush
Published 2018

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

by Kharas, Michael G., Lengner, Christopher J., Al-Shahrour, Fatima, Bullinger, Lars, Ball, Brian, Zaidi, Samir, Morgan, Kelly, Tam, Winnie, Paktinat, Mahnaz, Okabe, Rachel, Gozo, Maricel, Einhorn, William S., Lane, Steven W., Scholl, Claudia, Frohling, Stefan, Fleming, Mark, Ebert, Benjamin L., Gilliland, D. Gary, Jaenisch, Rudolf, Daley, George Q.
Published 2012

T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell

by Serwold, T., Hochedlinger, K., Swindle, J., Hedgpeth, J., Weissman, I. L., Jaenisch, Rudolf
Published 2018

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function

by Tao, Jifang, Hu, Keping, Chang, Qiang, Wu, Hao, Sherman, Nicholas E., Martinowich, Keri, Klose, Robert J., Schanen, Carolyn, Jaenisch, Rudolf, Wang, Weidong, Sun, Yi Eve
Published 2009

Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

by Pontis, Julien, Planet, Evarist, Offner, Sandra, Turelli, Priscilla, Duc, Julien, Coudray, Alexandre, Theunissen, Thorold W., Jaenisch, Rudolf, Trono, Didier
Published 2020

Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells

by Carey, Bryce W., Markoulaki, Styliani, Hanna, Jacob, Faddah, Dina A., Buganim, Yosef, Kim, Jongpil, Ganz, Kibibi, Steine, Eveline J, Cassady, John P., Creyghton, Menno P., Welstead, G. Grant, Gao, Qing, Jaenisch, Rudolf
Published 2015

Blimp1 Expression Predicts Embryonic Stem Cell Development In Vitro

by Chu, Li-Fang, Surani, M. Azim, Jaenisch, Rudolf, Zwaka, Thomas P
Published 2014

Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells

by Staerk, Judith, Dawlaty, Meelad M., Gao, Qing, Maetzel, Dorothea, Hanna, Jacob, Sommer, Cesar A., Mostoslavsky, Gustavo, Jaenisch, Rudolf
Published 2015

YY1 Is a Structural Regulator of Enhancer-Promoter Loops

by Sigova, Alla A., Hannett, Nancy M., Day, Daniel S., Abraham, Brian J., Cohen, Malkiel A., Nabet, Behnam, Buckley, Dennis L., Guo, Yang Eric, Hnisz, Denes, Bradner, James E., Gray, Nathanael S., Weintraub, Abraham Selby, Li, Charles Han, Zamudio Montes de Oca, Alicia, Jaenisch, Rudolf, Young, Richard A.
Published 2018

Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells

by Maetzel, Dorothea, Sarkar, Sovan, Wang, Haoyi, Abi-Mosleh, Lina, Xu, Ping, Gao, Qing, Mitalipova, Maisam, Jaenisch, Rudolf, Cheng, Albert Wu
Published 2015

TCRβ Feedback Signals Inhibit the Coupling of Recombinationally Accessible Vβ14 Segments with DJβ Complexes

by Jaenisch, Rudolf, Yang-Iott, Katherine S., Carpenter, Andrea C., Rowh, Marta A. W., Steinel, Natalie, Brady, Brenna L., Hochedlinger, Konrad, Bassing, Craig H.
Published 2012

Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus

by Dougan, Stephanie K., Ashour, Joseph, Karssemeijer, Roos A., Popp, Maximilian W., Avalos, Ana M., Barisa, Marta, Altenburg, Arwen F., Ingram, Jessica R., Cragnolini, Juan J., Guo, Chunguang, Alt, Frederick W., Jaenisch, Rudolf, Ploegh, Hidde
Published 2015

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

by Carroll, Bernadette, Maetzel, Dorothea, Otten, Gisela, Ratcliff, Matthew, Jaenisch, Rudolf, Sarkar, Sovan, Maddocks, Oliver D. K., Smith, Graham R., Dunlop, Elaine A., Passos, Joao F., Davies, Owen R., Tee, Andrew R., Korolchuk, Viktor I.
Published 2016