Enrichment of Extracellular Matrix Proteins from Tissues and Digestion into Peptides for Mass Spectrometry Analysis

by Clauser, Karl R., Naba, Alexandra, Hynes, Richard O.
Published 2017

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma

by Liu, Hui, Ong, Shao-En, Badu-Nkansah, Kwabena, Schindler, Jeffrey W., White, Forest M., Hynes, Richard O
Published 2011

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

by Reitman, Zachary J., Paolella, Brenton R., Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Sinai, Claire E., Malkin, Hayley, Huang, Ying, Grimmet, Leslie, Herbert, Zachary T., Sun, Yu, Weatherbee, Jessica L., Alberta, John A., Daley, John F., Rozenblatt-Rosen, Orit, Condurat, Alexandra L., Qian, Kenin, Khadka, Prasidda, Segal, Rosalind A., Haas-Kogan, Daphne, Filbin, Mariella G., Suva, Mario L., Regev, Aviv, Stiles, Charles D., Kieran, Mark W., Goumnerova, Liliana, Ligon, Keith L., Shalek, Alexander K, Bandopadhayay, Pratiti, Beroukhim, Rameen
Published 2020

CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus

by Shlomai, Amir, Michailidis, Eleftherios, Bhatta, Ankit, Rice, Charles M., Ramanan, Vyas, Cox, David Benjamin Turitz, Scott, David Arthur, Zhang, Feng, Bhatia, Sangeeta N, Schwartz, Robert E.
Published 2017

Nuclear Factor I/B is an Oncogene in Small Cell Lung Cancer

by Dooley, Alison L., Winslow, Monte Meier, Chiang, Derek Y., Banerji, Shantanu, Stransky, Nicolas, Dayton, Talya Lucia, Snyder, Eric, Senna, Stephanie, Whittaker, Charles A., Bronson, Roderick T., Crowley, Denise G., Barretina, Jordi, Garraway, Levi A., Meyerson, Matthew L., Jacks, Tyler E
Published 2011

Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

by Cao, Y., Raddassi, K., Nepom, G. T., Kwok, W. W., Goods, Brittany A., Love, John C, Hafler, David A.
Published 2017

Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition

by Siegrist, M. Sloan, Steigedal, Magnus, Ahmad, Rushdy, Mehra, Alka, Dragset, Marte S., Schuster, Brian M., Philips, Jennifer A., Rubin, Eric J., Carr, Steven A
Published 2014

An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling

by Yosef, Nir, Qiao, Jana, Raychowdhury, Raktima, Maritzen, Tanja, Haucke, Volker, Satoh, Takashi, Akira, Shizuo, Mertins, Philipp, Przybylski, Dariusz, Eisenhaure, Thomas, Carr, Steven A, Regev, Aviv, Hacohen, Nir, Chevrier, Nicolas, Clauser, Karl R.
Published 2018

Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging

by Schuerle, Simone, Furubayashi, Maiko, Soleimany, Ava P., Gwisai, Tinotenda, Huang, Wei, Voigt, Christopher A., Bhatia, Sangeeta N
Published 2020

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

by Venteicher, Andrew S., Tirosh, Itay, Hebert, Christine, Yizhak, Keren, Neftel, Cyril, Filbin, Mariella G., Hovestadt, Volker, Escalante, Leah E., Shaw, McKenzie L., Rodman, Christopher, Gillespie, Shawn M., Luo, Christina C., Ravichandran, Hiranmayi, Mylvaganam, Ravindra, Mount, Christopher, Onozato, Maristela L., Nahed, Brian V., Wakimoto, Hiroaki, Curry, William T., Iafrate, A. John, Rivera, Miguel N., Frosch, Matthew P., Brastianos, Priscilla K., Patel, Anoop P., Monje, Michelle, Cahill, Daniel P., Rozenblatt-Rosen, Orit, Louis, David N., Suvà, Mario L., Dionne, Danielle, Golub, Todd, Getz, Gad Asher, Regev, Aviv, Bernstein, Bradley E.
Published 2018

A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

by Reiling, Jan H., Clish, Clary, Carette, Jan E., Varadarajan, Malini, Brummelkamp, Thijn R., Sabatini, David
Published 2012

Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

by Burkard, Mark E., Maciejowski, John, Rodriguez-Bravo, Veronic, Repka, Michael, Lowery, Drew M., Clauser, Karl R., Shokat, Kevan M., Jallepalli, Prasad V., Zhang, Chao, Ph. D. Massachusetts Institute of Technology, Carr, Steven A, Yaffe, Michael B
Published 2010

Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

by Burkard, Mark E., Maciejowski, John, Rodriguez-Bravo, Veronica, Repka, Michael, Lowery, Drew M., Clauser, Karl R., Shokat, Kevan M., Jallepalli, Prasad V., Zhang, Chao, Ph. D. Massachusetts Institute of Technology, Carr, Steven A, Yaffe, Michael B
Published 2010

Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis

by Lee, Kyungheon, Song, Jun, Weissleder, Ralph, Lee, Hakho, Chen, Sidi, Sanjana, Neville E, Zheng, Kaijie, Shalem, Ophir, Shi, Xi, Scott, David Arthur, Pan, Jennifer Q., Zhang, Feng, Sharp, Phillip A.
Published 2017

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

by Munschauer, Mathias, Nguyen, Celina T., Sirokman, Klara, Hartigan, Christina R., Hogstrom, Larson, Engreitz, Jesse Michael, Ulirsch, Jacob C., Fulco, Charles P., Subramanian, Vidya, Chen, Jenny, Schenone, Monica, Guttman, Mitchell, Carr, Steven A, Lander, Eric Steven
Published 2020

Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus

by Sangesland, Maya, Ronsard, Larance, Kazer, Samuel Weisgurt, Bals, Julia, Boyoglu-Barnum, Seyhan, Yousif, Ashraf S., Barnes, Ralston, Feldman, Jared, Quirindongo-Crespo, Maricel, McTamney, Patrick M., Rohrer, Daniel, Lonberg, Nils, Chackerian, Bryce, Graham, Barney S., Kanekiyo, Masaru, Shalek, Alexander K, Lingwood, Daniel
Published 2020

Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells

by Chen, Pan-Yu, Muzumdar, Mandar, Dorans, Kimberly, Robbins, Rebecca, Bhutkar, Arjun, Del Rosario, Amanda M, Mertins, Philipp, Qiao, Jana, Schafer, Anette Claudia, Gertler, Frank, Carr, Steven A, Jacks, Tyler E
Published 2020

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver

by Naba, Alexandra, Clauser, Karl R., Whittaker, Charles A., Carr, Steven A., Tanabe, Kenneth K., Hynes, Richard O
Published 2014

Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity

by Saenz-Vash, Veronica, Romer, Katherine A., Xu, Shangzhe, Yesilaltay, Ayce, Krieger, Monty, Yu, Miao, Nieland, Thomas J, Penman, Marsha L, Carr, Steven A
Published 2012

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

by Ardain, Amanda, Domingo-Gonzalez, Racquel, Das, Shibali, Kazer, Samuel Weisgurt, Howard, Nicole C., Singh, Alveera, Ahmed, Mushtaq, Nhamoyebonde, Shepherd, Rangel-Moreno, Javier, Ogongo, Paul, Lu, Lan, Ramsuran, Duran, de la Luz Garcia-Hernandez, Maria, K. Ulland, Tyler, Darby, Matthew, Park, Eugene, Karim, Farina, Melocchi, Laura, Madansein, Rajhmun, Dullabh, Kaylesh Jay, Dunlap, Micah, Marin-Agudelo, Nancy, Ebihara, Takashi, Ndung'u, Thumbi, Kaushal, Deepak, Pym, Alexander S., Kolls, Jay K., Steyn, Adrie, Zuniga, Joaquin, Horsnell, William, Yokoyama, Wayne M., Shalek, Alexander K, Kloverpris, Henrik N., Colonna, Marco, Leslie, Alasdair, Khader, Shabaana A.
Published 2020