The Genetic Association of Variants in CD6, TNFRSF1A and IRF8 to Multiple Sclerosis: A Multicenter Case-Control Study

by Hafler, David A.
Published 2012

Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells

by Ploegh, Hidde, Costantino, Cristina Maria, Hafler, David A.
Published 2012

Class II MHC Self-Antigen Presentation in Human B and T Lymphocytes

by Costantino, Cristina Maria, Hafler, David A., Spooner, Eric, Ploegh, Hidde
Published 2012

NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data

by He, Liang, Davila-Velderrain, Jose, Sumida, Tomokazu S, Hafler, David A, Kellis, Manolis, Kulminski, Alexander M
Published 2022

Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving

by Han, Qing, Bradshaw, Elizabeth M., Nilsson, Bjorn, Hafler, David A., Love, J. Christopher, Nilsson, Bjorn
Published 2013

Role of "Western Diet" in Inflammatory Autoimmune Diseases

by Manzel, Arndt, Muller, Dominik N., Hafler, David A., Linker, Ralf A., Kleinewietfeld, Markus, Erdman, Susan E
Published 2016

Polyfunctional responses by human T cells result from sequential release of cytokines

by Bagheri, Nada, Lauffenburger, Douglas A., Love, J. Christopher, Bradshaw, Elizabeth M., Hafler, David A., Han, Qing
Published 2012

Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

by Cao, Y., Raddassi, K., Nepom, G. T., Kwok, W. W., Goods, Brittany A., Love, John C, Hafler, David A.
Published 2017

On-Chip Activation and Subsequent Detection of Individual Antigen-Specific T Cells

by Song, Qing, Han, Qing, Bradshaw, Elizabeth M., Kent, Sally C., Raddassi, Khadir, Nilsson, Bjorn, Nepom, Gerald T., Hafler, David A., Love, J. Christopher
Published 2013

Functional differences between PD-1⁺ and PD-1⁻CD4⁺ effector T cells in healthy donors and patients with glioblastoma multiforme

by Hernandez, Amanda L., Lowther, Daniel E., Lucca, Liliana E., Lerner, Benjamin A., Gunel, Murat, Raddassi, Khadir, Coric, Vlad, Hafler, David A., Thomas, Brittany A., Love, John C
Published 2017

Induction and molecular signature of pathogenic T[subscript H]17 cells

by Lee, Youjin, Awasthi, Amit, Yosef, Nir, Quintana, Francisco J., Xiao, Sheng, Peters, Anneli, Wu, Chuan, Kleinewietfeld, Markus, Kunder, Sharon, Hafler, David A., Sobel, Raymond A., Regev, Aviv, Kuchroo, Vijay K.
Published 2014

Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

by Jiang, Ruoyi, Meng, Hailong, Raddassi, Khadir, Fleming, Ira, Hoehn, Kenneth B, Dardick, Kenneth R, Belperron, Alexia A, Montgomery, Ruth R, Shalek, Alex K, Hafler, David A, Kleinstein, Steven H, Bockenstedt, Linda K
Published 2022

Automated high-dimensional flow cytometric data analysis

by Pyne, Saumyadipta, Hu, Xinli, Wang, Kui, Rossin, Elizabeth, Lin, Tsung-I, Maier, Lisa M., Baecher-Allan, Clare, McLachlan, Geoffrey J., Tamayo, Pablo, Hafler, David A., De Jager, Philip L., Mesirov, Jill P.
Published 2010

Microbial Reprogramming Inhibits Western Diet-Associated Obesity

by Poutahidis, Theofilos, Kleinewietfeld, Markus, Levkovich, Tatiana, Bhela, Siddheshvar, Chatzigiagkos, Antonis, Hafler, David A., Alm, Eric J., Erdman, Susan E., Varian, Bernard, Ibrahim, Yassin, Lakritz, Jessica, Kearney, Sean Michael, Smillie, Chris Scott, Perrotta, Allison Rose
Published 2013

TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage

by Taylor, Roslyn A., Chang, Che-Feng, Hammond, Matthew D., Grory, Brian Mac, Ai, Youxi, Steinschneider, Arthur F., Renfroe, Stephen C., Askenase, Michael H., McCullough, Louise D., Kasner, Scott E., Mullen, Michael T., Hafler, David A., Sansing, Lauren H., Love, John C, Goods, Brittany A.
Published 2017

IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production

by Maier, Lisa M., Lowe, Christopher E., Cooper, Jason, Downes, Kate, Anderson, David E., Severson, Christopher, Clark, Pamela M., Healy, Brian, Walker, Neil, Aubin, Cristin, Oksenberg, Jorge R., Hauser, Stephen L., Compston, Alastair, Sawcer, Stephen, De Jager, Philip L., Wicker, Linda S., Todd, John A., Hafler, David A.
Published 2010

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

by Patsopoulos, Nikolaos A., Barcellos, Lisa F., Hintzen, Rogier Q., Schaefer, Catherine, van Duijn, Cornelia M., Noble, Janelle A., Raj, Towfique, Gourraud, Pierre-Antoine, Stranger, Barbara E., Oksenberg, Jorge, Olsson, Tomas, Taylor, Bruce V., Sawcer, Stephen, Hafler, David A., Carrington, Mary, De Jager, Philip L., de Bakker, Paul I. W.
Published 2013

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

by Lee, M. N., Ye, C., Villani, A.-C, Raj, T., Li, W., Eisenhaure, Thomas, Imboywa, S. H., Chipendo, P. I., Slowikowski, K., Raddassi, K., McCabe, C., Lee, M. H., Frohlich, I. Y., Raychaudhuri, S., Stranger, B. E., Benoist, Christophe, De Jager, Philip L., Hacohen, Nir, Ran, F. Ann, Zhang, Feng, Regev, Aviv, Hafler, David A., Ward, Lucas D., Kellis, Manolis
Published 2015

Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms

by Xiao, Sheng, Yosef, Nir, Yang, Jianfei, Wang, Yonghui, Zhou, Ling, Zhu, Chen, Wu, Chuan, Baloglu, Erkan, Schmidt, Darby, Ramesh, Radha, Lobera, Mercedes, Sundrud, Mark S, Tsai, Pei-Yun, Xiang, Zhijun, Wang, Jinsong, Xu, Yan, Lin, Xichen, Kretschmer, Karsten, Rahl, Peter B, Zhong, Zhong, Hafler, David A, Ghosh, Shomir, Marson, Alexander, Kuchroo, Vijay K, Regev, Aviv, Young, Richard A.
Published 2017

Pervasive Sharing of Genetic Effects in Autoimmune Disease

by Cotsapas, Chris, Voight, Benjamin F., Lage, Kasper, Neale, Benjamin M., Wallace, Chris, Abecasis, Gonçalo R., Barrett, Jeffrey C., Behrens, Timothy, Cho, Judy, Jager, Philip L. De, Elder, James T., Graham, Robert R., Gregersen, Peter K., Klareskog, Lars, Siminovitch, Katherine A., Heel, David A. van, Wijmenga, Cisca, Worthington, Jane, Todd, John A., Hafler, David A., Rich, Stephen S., Daly, Mark J., Rossin, Elizabeth
Published 2012