Showing 1 - 20 results of 21 for search '"knockout"', query time: 0.37s Refine Results
  1. 1
    Differential Expression Profiles and Functional Prediction of Circular RNAs and Long Non-coding RNAs in the Hippocampus of Nrf2-Knockout Mice
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  2. 2
    Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
    “... cysts, and colonic polyps/cancers. By combining Gateway Technology with the Ksp-Cre gene knockout system...”
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    Article
  3. 3
    Gαq Regulates the Development of Rheumatoid Arthritis by Modulating Th1 Differentiation
    by Dashan Wang, Yuan Liu, Yan Li, Yan He, Jiyun Zhang, Guixiu Shi
    Published 2017-01-01
    “... in differentiation of Th1 cells. By using Gαq knockout (Gnaq−/−) mice, we demonstrated that loss of Gαq led...”
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  4. 4
    Activity- and sleep-dependent regulation of tonic inhibition by Shisa7
    by Kunwei Wu, Wenyan Han, Qingjun Tian, Yan Li, Wei Lu
    Published 2021-03-01
    “... in hippocampal neurons. In juvenile Shisa7 knockout (KO) mice, α5-GABAAR-mediated tonic currents...”
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    Article
  5. 5
    Arhgef2 regulates neural differentiation in the cerebral cortex through mRNA m6A-methylation of Npdc1 and Cend1
    “... methylation. Arhgef2 knockout decreases expression of Mettl14 and total m6A level significantly...”
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    Article
  6. 6
    Novel application of neural network modelling for multicomponent herbal medicine optimization
    “... as “components knockout” samples, was chosen as the case study. The chemical fingerprints of SAI were obtained...”
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  7. 7
    Complement Component C4 Regulates the Development of Experimental Autoimmune Uveitis through a T Cell-Intrinsic Mechanism
    “...-type (WT) and C4 knockout (KO) mice using indirect ophthalmoscopy, scanning laser ophthalmoscopy...”
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    Article
  8. 8
    Comparison and Validation of Putative Pathogenicity-Related Genes Identified by T-DNA Insertional Mutagenesis and Microarray Expression Profiling in Magnaporthe oryzae
    by Ying Wang, Ying Wáng, Qi Tan, Ying Nv Gao, Yan Li, Da Peng Bao
    Published 2017-01-01
    “..., and infection ability in their knockout mutants. Our results suggest that both of the lists might contain large...”
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    Article
  9. 9
    Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis
    “... autophagy to apoptosis. Unlike in vivo studies, we found that primary chondrocytes from α7-nAChRs knockout...”
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  10. 10
    Activation of α7-nAChRs Promotes the Clearance of α-Synuclein and Protects Against Apoptotic Cell Death Induced by Exogenous α-Synuclein Fibrils
    “... on the clearance of αSyn in normal and αSyn stably transduced SH-SY5Y cells. Moreover, using α7-nAChRs knockout...”
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  11. 11
    Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication
    “... IAVs. Here, we performed a genome-scale CRISPR/Cas9 knockout screen in human lung epithelial cells...”
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  12. 12
    miR-1224 contributes to ischemic stroke-mediated natural killer cell dysfunction by targeting Sp1 signaling
    “... on NK cell activity was blocked in Sp1 knockout mice. Conclusions These findings indicate that miR-1224...”
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  13. 13
    Effects of EFNA1 on cell phenotype and prognosis of esophageal carcinoma
    “... on bioinformatics, the functional background of EFNA1 overexpression was analyzed. EFNA1 knockout cell model...”
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  14. 14
    Pharmacological Blockade of Adenosine A2A but Not A1 Receptors Enhances Goal-Directed Valuation in Satiety-Based Instrumental Behavior
    “.... However, pharmacological blockade and genetic knockout of A1Rs did not affect acquisition or sensitivity...”
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  15. 15
    Evolution and Functional Divergence of SUN Genes in Plants
    “.../Cas9-mediated knockout of GbSUN5 both showed higher ratios of aborted seeds, although pollen viability...”
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  16. 16
    APICAL SPIKELET ABORTION (ASA) Controls Apical Panicle Development in Rice by Regulating Salicylic Acid Biosynthesis
    “... and in OsASA-knockout plants. Collectively, these results suggest that the boron distribution maintained...”
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    Article
  17. 17
    Fine-Tuning Roles of Osa-miR159a in Rice Immunity Against Magnaporthe oryzae and Development
    “...) to block Osa-miR159a showed enhanced susceptibility. Knockout mutations of the target genes of Osa-miR159a...”
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    Article
  18. 18
    Hexokinases link DJ-1 to the PINK1/parkin pathway
    “... to probe the mechanisms involved. Results We find that in both rat and mouse brains, DJ-1 knockout results...”
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  19. 19
    Inhibiting miR-22 Alleviates Cardiac Dysfunction by Regulating Sirt1 in Septic Cardiomyopathy
    “.... miR-22 cardiac-specific knockout (miR-22cKO) mice and miR-22 cardiac-specific transgenic (miR-22cOE...”
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  20. 20
    Genetic ablation of dynactin p150Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice
    “...1-Cre mice to generate the bigenic p150Glued (Dctn1 LoxP/LoxP; Thy1-Cre) conditional knockout (cKO...”
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