adolescent controlled study human 128 randomized controlled trial Humans 123 Adolescent 122 female 114 male 112 Female 105 Male 102 adult 88 Young Adult 77 young adult 77 Adult 72 procedures 48 middle aged 43 Middle Aged 42 child 40 treatment outcome 36 psychology 35 Treatment Outcome 32 Child 31 major clinical study 29 Article 27 aged 23 article 23 Double-Blind Method 22 double blind procedure 22 Aged 21 comparative study 20