genome-wide association study phenotype 3 single nucleotide polymorphism 3 Article 2 genetic epidemiology 2 genetic risk 2 genetic variability 2 human 2 Application fields 1 Architecture 1 Benchmarking 1 Biological mechanisms 1 COVID-19 1 Crohn disease 1 Diagnostic and Statistical Manual of Mental Disorders 1 Genetic epidemiology 1 Genetic variants 1 Genome-Wide Association Study 1 Genome-wide association studies 1 High dimensional data 1 International Classification of Diseases 1 Lasso Penalization 1 Least squares approximations 1 Least-Squares Analysis 1 Meta-analysis 1 Oncology 1 Partial Least Square 1 Partial least square (PLS) 1 Pathway analysis 1 Penalized partial least squares 1