Pharmacokinetic drug interactions of integrase strand transfer inhibitors

by Chi-Hua Lu, Edward M. Bednarczyk, Linda M. Catanzaro, Alyssa Shon, Jia-Chen Xu, Qing Ma
Published 2021-01-01

Can NLRP3 inhibitors improve on dexamethasone for the treatment of COVID-19?

by Alexander Hooftman, Luke A.J. O'Neill
Published 2021-01-01

Artificial intelligence-driven drug repurposing and structural biology for SARS-CoV-2

by Kartikay Prasad, Vijay Kumar
Published 2021-01-01

Crosstalk between anticancer drugs and mitochondrial functions

by Kuleshwar Sahu, Urvashi Langeh, Charan Singh, Arti Singh, PHD
Published 2021-01-01

Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside

by Sijia Tao, Keivan Zandi, Leda Bassit, Yee Tsuey Ong, Kiran Verma, Peng Liu, Jessica A. Downs-Bowen, Tamara McBrayer, Julia C. LeCher, James J. Kohler, Philip R. Tedbury, Baek Kim, Franck Amblard, Stefan G. Sarafianos, Raymond F. Schinazi
Published 2021-01-01

Prostate cancer: Therapeutic prospect with herbal medicine

by Suvranil Ghosh, Joyita Hazra, Koustav Pal, Vinod K. Nelson, Mahadeb Pal
Published 2021-01-01

Screening of phytoconstituents of Andrographis paniculata against various targets of Japanese encephalitis virus: An in-silico and in-vitro target-based approach

by Shailesh Bhosale, Anoop Kumar
Published 2021-01-01

The potential roles of Nrf2/Keap1 signaling in anticancer drug interactions

by Jingya Wang, Jin Yang, Mingnan Cao, Zhigang Zhao, Baoshan Cao, Siwang Yu
Published 2021-01-01

Pharmacogenomics and circadian rhythms as mediators of cardiovascular drug-drug interactions

by Yong-Jian Geng, Rosalinda Madonna, Ramon C. Hermida, Michael H. Smolensky
Published 2021-01-01

Teriflunomide: A possible effective drug for the comprehensive treatment of COVID-19

by Amgad M. Rabie
Published 2021-01-01

Can the application of graphene oxide contribute to the fight against COVID-19? Antiviral activity, diagnosis and prevention

by Asmaa Rhazouani, Khalid Aziz, Halima Gamrani, Lhoucine Gebrati, Md Sahab Uddin, Aziz Faissal
Published 2021-01-01

ATP citrate lyase inhibitor Bempedoic Acid alleviate long term HFD induced NASH through improvement in glycemic control, reduction of hepatic triglycerides & total cholesterol,...

by K.V. Sanjay, Santosh Vishwakarma, Bharat Ravindra Zope, Vishal Subhash Mane, Sunil Mohire, Saravanakumar Dhakshinamoorthy
Published 2021-01-01

The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells

by Abel M. Mengeste, Jenny Lund, Parmeshwar Katare, Roya Ghobadi, Hege G. Bakke, Per Kristian Lunde, Lars Eide, Gavin O’ Mahony, Sven Göpel, Xiao-Rong Peng, Eili Tranheim Kase, G. Hege Thoresen, Arild C. Rustan
Published 2021-01-01

Interaction of obtusilactone B and related butanolide lactones with the barrier-to-autointegration factor 1 (BAF1). A computational study

by Christian Bailly, Gérard Vergoten
Published 2021-01-01

Protective effect of co-administration of caffeine and piracetam on scopolamine-induced amnesia in Wistar rats

by Subhash Chaturvedi, Aditya Ganeshpurkar, Abhishek Shrivastava, Nazneen Dubey
Published 2021-01-01

Exploring new Horizons in overcoming P-glycoprotein-mediated multidrug-resistant breast cancer via nanoscale drug delivery platforms

by Paras Famta, Saurabh Shah, Essha Chatterjee, Hoshiyar Singh, Biswajit Dey, Santosh Kumar Guru, Shashi Bala Singh, Saurabh Srivastava
Published 2021-01-01

Host directed therapies: COVID-19 and beyond

by Devavrat Tripathi, Megha Sodani, Pramod Kumar Gupta, Savita Kulkarni
Published 2021-01-01

SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells

by Jenny Lund, Solveig A. Krapf, Medina Sistek, Hege G. Bakke, Stefano Bartesaghi, Xiao-Rong Peng, Arild C. Rustan, G. Hege Thoresen, Eili T. Kase
Published 2021-01-01

Physiopathology and prospectives for therapeutic treatment of pulmonary fibrotic state in COVID-19 patients

by Antonio Vitiello, Francesco Ferrara
Published 2021-01-01

Mitochondrial dysfunction and oxidative stress are involved in the mechanism of tramadol-induced renal injury

by Khadijah Mousavi, Ram Kumar Manthari, Asma Najibi, Zhipeng Jia, Mohammad Mehdi Ommati, Reza Heidari
Published 2021-01-01