Potential drug–drug interactions between antiretroviral therapy and treatment regimens for multi-drug resistant tuberculosis: Implications for HIV care of MDR-TB co-infected indivi...

by Jackson Mukonzo, Eleni Aklillu, Vincent Marconi, Raymond F. Schinazi
Published 2019-06-01

Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance

by Nicole Bertoletti, Albert H. Chan, Raymond F. Schinazi, Karen S. Anderson
Published 2020-10-01

SAMHD1 Functions and Human Diseases

by Si’Ana A. Coggins, Bijan Mahboubi, Raymond F. Schinazi, Baek Kim
Published 2020-03-01

Host SAMHD1 protein restricts endogenous reverse transcription of HIV-1 in nondividing macrophages

by Bijan Mahboubi, Christina Gavegnano, Dong-Hyun Kim, Raymond F. Schinazi, Baek Kim
Published 2018-10-01

Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome.

by Ila R Singh, John E Gorzynski, Daria Drobysheva, Leda Bassit, Raymond F Schinazi
Published 2010-04-01

Residual viremia in an RT-SHIV rhesus macaque HAART model marked by the presence of a predominant plasma clone and a lack of viral evolution.

by Robert C Kauffman, Andradi Villalobos, Joanne H Bowen, Lourdes Adamson, Raymond F Schinazi
Published 2014-01-01

The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model

by Woldeab B. Haile, Christina Gavegnano, Sijia Tao, Yong Jiang, Raymond F. Schinazi, William R. Tyor
Published 2016-08-01

Effect of induced dNTP pool imbalance on HIV-1 reverse transcription in macrophages

by Caitlin Shepard, Joella Xu, Jessica Holler, Dong-Hyun Kim, Louis M. Mansky, Raymond F. Schinazi, Baek Kim
Published 2019-10-01

Baricitinib reverses HIV-associated neurocognitive disorders in a SCID mouse model and reservoir seeding in vitro

by Christina Gavegnano, Woldeab B. Haile, Selwyn Hurwitz, Sijia Tao, Yong Jiang, Raymond F. Schinazi, William R. Tyor
Published 2019-09-01

Synthesis of 4′-Substituted-2′-Deoxy-2′-α-Fluoro Nucleoside Analogs as Potential Antiviral Agents

by Mahesh Kasthuri, Chengwei Li, Kiran Verma, Olivia Ollinger Russell, Lyndsey Dickson, Louise McCormick, Leda Bassit, Franck Amblard, Raymond F. Schinazi
Published 2020-03-01

Jak Inhibitors Modulate Production of Replication Competent Zika Virus in Human Hofbauer, Trophoblasts, and Neuroblastoma cells

by Christina Gavegnano, Leda C. Bassit, Bryan D. Cox, Hui-Mien Hsiao, Erica L. Johnson, Mehul Suthar, Rana Chakraborty, Raymond F. Schinazi
Published 2017-05-01

Viral decay kinetics in the highly active antiretroviral therapy-treated rhesus macaque model of AIDS.

by Jesse D Deere, Joanne Higgins, Elda Cannavo, Andradi Villalobos, Lourdes Adamson, Emilie Fromentin, Raymond F Schinazi, Paul A Luciw, Thomas W North
Published 2010-07-01

Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART.

by Jesse D Deere, Robert C Kauffman, Elda Cannavo, Joanne Higgins, Andradi Villalobos, Lourdes Adamson, Raymond F Schinazi, Paul A Luciw, Thomas W North
Published 2014-01-01

Substrates and Inhibitors of SAMHD1.

by Joseph A Hollenbaugh, Jadd Shelton, Sijia Tao, Sheida Amiralaei, Peng Liu, Xiao Lu, Russell W Goetze, Longhu Zhou, James H Nettles, Raymond F Schinazi, Baek Kim
Published 2017-01-01

Studies on the Efficacy, Potential Cardiotoxicity and Monkey Pharmacokinetics of GLP-26 as a Potent Hepatitis B Virus Capsid Assembly Modulator

by Selwyn J. Hurwitz, Noreen McBrearty, Alla Arzumanyan, Eugene Bichenkov, Sijia Tao, Leda Bassit, Zhe Chen, James J. Kohler, Franck Amblard, Mark A. Feitelson, Raymond F. Schinazi
Published 2021-01-01

Synthesis and Antiviral Evaluation of (1,4-Disubstituted-1,2,3-Triazol)-<i>(E)</i>-2-Methyl-but-2-Enyl Nucleoside Phosphonate Prodrugs

by Tuniyazi Abuduaini, Vincent Roy, Julien Marlet, Catherine Gaudy-Graffin, Denys Brand, Cécile Baronti, Franck Touret, Bruno Coutard, Tamara R. McBrayer, Raymond F. Schinazi, Luigi A. Agrofoglio
Published 2021-03-01

Non-alcoholic fatty liver disease is a risk factor for occurrence of hepatocellular carcinoma after sustained virologic response in chronic hepatitis C patients: A prospective four...

by Dong Ji, Guo-feng Chen, Xiao-xia Niu, Mingjie Zhang, Cheng Wang, Qing Shao, Vanessa Wu, Yudong Wang, Gregory Cheng, Selwyn J. Hurwitz, Raymond F. Schinazi, George Lau
Published 2021-06-01

Encephalopathy and Encephalitis Associated with Cerebrospinal Fluid Cytokine Alterations and Coronavirus Disease, Atlanta, Georgia, USA, 2020

by Karima Benameur, Ankita Agarwal, Sara C. Auld, Matthew P. Butters, Andrew S. Webster, Tugba Ozturk, J. Christina Howell, Leda C. Bassit, Alvaro Velasquez, Raymond F. Schinazi, Mark E. Mullins, William T. Hu
Published 2020-09-01

Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.

by Debra A Wadford, Robert C Kauffman, Jesse D Deere, Scott T Aoki, Richard A Stanton, Joanne Higgins, Koen K A Van Rompay, Andradi Villalobos, James H Nettles, Raymond F Schinazi, Niels C Pedersen, Thomas W North
Published 2014-01-01

Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase

by Keivan Zandi, Katie Musall, Adrian Oo, Dongdong Cao, Bo Liang, Pouya Hassandarvish, Shuiyun Lan, Ryan L. Slack, Karen A. Kirby, Leda Bassit, Franck Amblard, Baek Kim, Sazaly AbuBakar, Stefan G. Sarafianos, Raymond F. Schinazi
Published 2021-04-01