Comparative production analysis of three phlebovirus nucleoproteins under denaturing or non-denaturing conditions for crystallographic studies.

by Violaine Lantez, Karen Dalle, Rémi Charrel, Cécile Baronti, Bruno Canard, Bruno Coutard
Published 2011-01-01

Characterisation of Structural Proteins from Chronic Bee Paralysis Virus (CBPV) Using Mass Spectrometry

by Aurore Chevin, Bruno Coutard, Philippe Blanchard, Anne-Sophie Dabert-Gay, Magali Ribière-Chabert, Richard Thiéry
Published 2015-06-01

The Cytotoxic Effect of <i>Apis mellifera</i> Venom with a Synergistic Potential of Its Two Main Components—Melittin and PLA2—On Colon Cancer HCT116 Cell Lines

by Carole Yaacoub, Mariam Rifi, Dany El-Obeid, Hiba Mawlawi, Jean-Marc Sabatier, Bruno Coutard, Ziad Fajloun
Published 2021-04-01

The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes.

by François Ferron, Zongli Li, Eric I Danek, Dahai Luo, Yeehwa Wong, Bruno Coutard, Violaine Lantez, Rémi Charrel, Bruno Canard, Thomas Walz, Julien Lescar
Published 2011-05-01

Development and Evaluation of a duo SARS-CoV-2 RT-qPCR Assay Combining Two Assays Approved by the World Health Organization Targeting the Envelope and the RNA-Dependant RNA Polymer...

by Laura Pezzi, Remi N. Charrel, Laetitia Ninove, Antoine Nougairede, Gregory Molle, Bruno Coutard, Guillaume Durand, Isabelle Leparc-Goffart, Xavier de Lamballerie, Laurence Thirion
Published 2020-06-01

High specificity and sensitivity of Zika EDIII-based ELISA diagnosis highlighted by a large human reference panel.

by Jessica Denis, Sarah Attoumani, Patrick Gravier, Bernard Tenebray, Annabelle Garnier, Sébastien Briolant, Franck de Laval, Véronique Chastres, Gilda Grard, Isabelle Leparc-Goffart, Bruno Coutard, Cyril Badaut
Published 2019-09-01

Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.

by Etienne Decroly, Claire Debarnot, François Ferron, Mickael Bouvet, Bruno Coutard, Isabelle Imbert, Laure Gluais, Nicolas Papageorgiou, Andrew Sharff, Gérard Bricogne, Miguel Ortiz-Lombardia, Julien Lescar, Bruno Canard
Published 2011-05-01

Synthesis and Antiviral Evaluation of (1,4-Disubstituted-1,2,3-Triazol)-<i>(E)</i>-2-Methyl-but-2-Enyl Nucleoside Phosphonate Prodrugs

by Tuniyazi Abuduaini, Vincent Roy, Julien Marlet, Catherine Gaudy-Graffin, Denys Brand, Cécile Baronti, Franck Touret, Bruno Coutard, Tamara R. McBrayer, Raymond F. Schinazi, Luigi A. Agrofoglio
Published 2021-03-01

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

by Ashleigh Shannon, Barbara Selisko, Nhung-Thi-Tuyet Le, Johanna Huchting, Franck Touret, Géraldine Piorkowski, Véronique Fattorini, François Ferron, Etienne Decroly, Chris Meier, Bruno Coutard, Olve Peersen, Bruno Canard
Published 2020-09-01

The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription.

by Benjamin Morin, Bruno Coutard, Michaela Lelke, François Ferron, Romy Kerber, Saïd Jamal, Antoine Frangeul, Cécile Baronti, Rémi Charrel, Xavier de Lamballerie, Clemens Vonrhein, Julien Lescar, Gérard Bricogne, Stephan Günther, Bruno Canard
Published 2010-09-01

Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model

by Jean-Sélim Driouich, Maxime Cochin, Guillaume Lingas, Grégory Moureau, Franck Touret, Paul-Rémi Petit, Géraldine Piorkowski, Karine Barthélémy, Caroline Laprie, Bruno Coutard, Jérémie Guedj, Xavier de Lamballerie, Caroline Solas, Antoine Nougairède
Published 2021-03-01

Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination

by Ramona Mögling, Adam Meijer, Natasa Berginc, Sylvia Bruisten, Remi Charrel, Bruno Coutard, Isabella Eckerle, Vincent Enouf, Olav Hungnes, Gülay Korukluoglu, Thanos Kossyvakis, Andreas Mentis, Richard Molenkamp, Shaman Muradrasoli, Anna Papa, Fiona Pigny, Laurence Thirion, Sylvie van der Werf, Chantal Reusken
Published 2020-08-01

Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection.

by Rami Sommerstein, Lukas Flatz, Melissa M Remy, Pauline Malinge, Giovanni Magistrelli, Nicolas Fischer, Mehmet Sahin, Andreas Bergthaler, Sebastien Igonet, Jan Ter Meulen, Dorothée Rigo, Paolo Meda, Nadia Rabah, Bruno Coutard, Thomas A Bowden, Paul-Henri Lambert, Claire-Anne Siegrist, Daniel D Pinschewer
Published 2015-11-01

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

by Lonneke van der Linden, Laia Vives-Adrián, Barbara Selisko, Cristina Ferrer-Orta, Xinran Liu, Kjerstin Lanke, Rachel Ulferts, Armando M De Palma, Federica Tanchis, Nesya Goris, David Lefebvre, Kris De Clercq, Pieter Leyssen, Céline Lacroix, Gerhard Pürstinger, Bruno Coutard, Bruno Canard, David D Boehr, Jamie J Arnold, Craig E Cameron, Nuria Verdaguer, Johan Neyts, Frank J M van Kuppeveld
Published 2015-03-01

Evidence for novel hepaciviruses in rodents.

by Jan Felix Drexler, Victor Max Corman, Marcel Alexander Müller, Alexander N Lukashev, Anatoly Gmyl, Bruno Coutard, Alexander Adam, Daniel Ritz, Lonneke M Leijten, Debby van Riel, Rene Kallies, Stefan M Klose, Florian Gloza-Rausch, Tabea Binger, Augustina Annan, Yaw Adu-Sarkodie, Samuel Oppong, Mathieu Bourgarel, Daniel Rupp, Bernd Hoffmann, Mathias Schlegel, Beate M Kümmerer, Detlev H Krüger, Jonas Schmidt-Chanasit, Alvaro Aguilar Setién, Veronika M Cottontail, Thiravat Hemachudha, Supaporn Wacharapluesadee, Klaus Osterrieder, Ralf Bartenschlager, Sonja Matthee, Martin Beer, Thijs Kuiken, Chantal Reusken, Eric M Leroy, Rainer G Ulrich, Christian Drosten
Published 2013-01-01