Expression of immune checkpoints on circulating tumor cells in men with metastatic prostate cancer

by Tian Zhang, Anika Agarwal, R. Garland Almquist, Daniella Runyambo, Sally Park, Elizabeth Bronson, Rengasamy Boominathan, Chandra Rao, Monika Anand, Taofik Oyekunle, Patrick Healy, Megan A. McNamara, Kathryn Ware, Jason A. Somarelli, Daniel J. George, Andrew J. Armstrong
Published 2021-02-01

Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery

by Michael M. B. Green, Nelson Chao, Saurabh Chhabra, Kelly Corbet, Cristina Gasparetto, Ari Horwitz, Zhiguo Li, Jagadish Kummetha Venkata, Gwynn Long, Alice Mims, David Rizzieri, Stefanie Sarantopoulos, Robert Stuart, Anthony D. Sung, Keith M. Sullivan, Luciano Costa, Mitchell Horwitz, Yubin Kang
Published 2016-08-01

Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy

by Nicholas C. DeVito, Michael Sturdivant, Balamayooran Thievanthiran, Christine Xiao, Michael P. Plebanek, April K.S. Salama, Georgia M. Beasley, Alisha Holtzhausen, Veronica Novotny-Diermayr, John H. Strickler, Brent A. Hanks
Published 2021-05-01

The Durham Initiative for Stomach Health (DISH): a pilot community-based Helicobacter pylori education and screening study

by Sydnee Crankshaw, Julia Butt, Jennifer M. Gierisch, Nadine J. Barrett, Sabrena Mervin-Blake, Kevin Oeffinger, Steven Patierno, Valarie Worthy, Ronald Godbee, Meira Epplein
Published 2020-08-01

Anterior gland focal cryoablation: proof-of-concept primary prostate cancer treatment in select men with localized anterior cancers detected by multi-parametric magnetic resonance...

by Christina Sze, Efrat Tsivian, Kae Jack Tay, Ariel A. Schulman, Leah G. Davis, Rajan T. Gupta, Thomas J. Polascik
Published 2019-12-01

Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width

by Ziwei Dai, Samantha J. Mentch, Xia Gao, Sailendra N. Nichenametla, Jason W. Locasale
Published 2018-05-01

Differential angiogenic gene expression in TP53 wild-type and mutant ovarian cancer cell lines

by Brittany Anne Davidson, Jennifer eRubatt, David eCorcoran, Deanna eTeoh, Marcus eBernadini, Lisa eGrace, John William Soper, Andrew eBerchuck, Sharareh eSiamakpour-Reihani, Wei eChen, Kouros eOwzar, Susan eMurphy, Angeles Alvarez Secord
Published 2014-06-01

A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation

by Tyler A. Allen, Mark M. Cullen, Nathan Hawkey, Hiroyuki Mochizuki, Lan Nguyen, Elyse Schechter, Luke Borst, Jeffrey A. Yoder, Jennifer A. Freedman, Jennifer A. Freedman, Steven R. Patierno, Steven R. Patierno, Ke Cheng, Ke Cheng, William C. Eward, Jason A. Somarelli, Jason A. Somarelli
Published 2021-09-01

Prostate Cancer Cell Phenotypes Remain Stable Following PDE5 Inhibition in the Clinically Relevant Range

by William Hankey, Benjamin Sunkel, Fuwen Yuan, Haiyan He, Jennifer M. Thomas-Ahner, Zhong Chen, Steven K. Clinton, Jiaoti Huang, Qianben Wang
Published 2020-09-01

Assessing Cancer Risk Associated with Aquatic Polycyclic Aromatic Hydrocarbon Pollution Reveals Dietary Routes of Exposure and Vulnerable Populations

by Larisa M. Gearhart-Serna, Nishad Jayasundara, Moises Tacam, Richard Di Giulio, Gayathri R. Devi
Published 2018-01-01

Targeting One Carbon Metabolism with an Antimetabolite Disrupts Pyrimidine Homeostasis and Induces Nucleotide Overflow

by Zheng Ser, Xia Gao, Christelle Johnson, Mahya Mehrmohamadi, Xiaojing Liu, Siqi Li, Jason W. Locasale
Published 2016-06-01

An Aptamer for Broad Cancer Targeting and Therapy

by Bethany Powell Gray, Xirui Song, David S. Hsu, Christina Kratschmer, Matthew Levy, Ashley P. Barry, Bruce A. Sullenger
Published 2020-10-01

Role of Tumor-Mediated Dendritic Cell Tolerization in Immune Evasion

by Nicholas C. DeVito, Michael P. Plebanek, Bala Theivanthiran, Brent A. Hanks, Brent A. Hanks
Published 2019-12-01

Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence

by Andrea Walens, Jiaxing Lin, Jeffrey S. Damrauer, Brock McKinney, Ryan Lupo, Rachel Newcomb, Douglas B. Fox, Nathaniel W. Mabe, Jeremy Gresham, Zhecheng Sheng, Alexander B. Sibley, Tristan De Buysscher, Hemant Kelkar, Piotr A. Mieczkowski, Kouros Owzar, James V. Alvarez
Published 2020-10-01

Recurrent Extradural Myxopapillary Ependymoma With Oligometastatic Spread

by Kristen A. Batich, Kristen A. Batich, Kristen A. Batich, Richard F. Riedel, Richard F. Riedel, John P. Kirkpatrick, John P. Kirkpatrick, John P. Kirkpatrick, John P. Kirkpatrick, Betty C. Tong, Betty C. Tong, William C. Eward, William C. Eward, Char Loo Tan, Char Loo Tan, Patricia D. Pittman, Roger E. McLendon, Roger E. McLendon, Roger E. McLendon, Katherine B. Peters, Katherine B. Peters, Katherine B. Peters
Published 2019-11-01

Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism

by Mahya Mehrmohamadi, Lucas K. Mentch, Andrew G. Clark, Jason W. Locasale
Published 2016-12-01

Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

by Yun Feng, Yanru Wang, Hongliang Liu, Zhensheng Liu, Coleman Mills, Younghun Han, Rayjean J. Hung, Yonathan Brhane, John McLaughlin, Paul Brennan, Heike Bickeboeller, Albert Rosenberger, Richard S. Houlston, Neil E. Caporaso, Maria Teresa Landi, Irene Brueske, Angela Risch, Yuanqing Ye, Xifeng Wu, David C. Christiani, Christopher I. Amos, Qingyi Wei
Published 2017-04-01

Biomarkers of immunotherapy in urothelial and renal cell carcinoma: PD-L1, tumor mutational burden, and beyond

by Jason Zhu, Andrew J. Armstrong, Terence W. Friedlander, Won Kim, Sumanta K. Pal, Daniel J. George, Tian Zhang
Published 2018-01-01

Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma

by Mark Manzano, Ajinkya Patil, Alexander Waldrop, Sandeep S. Dave, Amir Behdad, Eva Gottwein
Published 2018-08-01

Strategies to Prevent Cardiovascular Toxicity in Breast Cancer: Is It Ready for Primetime?

by Robin Kikuchi, Nishant P. Shah, Susan F. Dent
Published 2020-03-01