Tislelizumab uniquely binds to the CC′ loop of PD‐1 with slow‐dissociated rate and complete PD‐L1 blockage

by Yuan Hong, Yingcai Feng, Hanzi Sun, Bo Zhang, Hongfu Wu, Qing Zhu, Yucheng Li, Tong Zhang, Yilu Zhang, Xinxin Cui, Zhuo Li, Xiaomin Song, Kang Li, Mike Liu, Ye Liu
Published 2021-03-01

NEK5 interacts with LonP1 and its kinase activity is essential for the regulation of mitochondrial functions and mtDNA maintenance

by Camila de Castro Ferezin, Fernanda Luisa Basei, Talita D. Melo‐Hanchuk, Ana Luisa deOliveira, Andressa Peres de Oliveira, Mateus P. Mori, Nadja C. deSouza‐Pinto, Jörg Kobarg
Published 2021-03-01

Cyclophilin D‐dependent mitochondrial permeability transition amplifies inflammatory reprogramming in endotoxemia

by Balazs Veres, Krisztian Eros, Csenge Antus, Nikoletta Kalman, Fruzsina Fonai, Peter Balazs Jakus, Eva Boros, Zoltan Hegedus, Istvan Nagy, Laszlo Tretter, Ferenc Gallyas Jr, Balazs Sumegi
Published 2021-03-01

Dysregulation of the Sirt5/IDH2 axis contributes to sunitinib resistance in human renal cancer cells

by Liang Meng, Deqiang Chen, Gaopei Meng, Li Lu, Chenggang Han
Published 2021-03-01

DNA methylation subtypes for ovarian cancer prognosis

by Lili Yin, Ningning Zhang, Qing Yang
Published 2021-03-01