Showing 1 - 18 results of 18 for search '"Hayflick limit"', query time: 0.76s Refine Results
  1. 1
    Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells
    by Christine A. Armstrong, Kazunori Tomita
    Published 2017-01-01
    Subjects: “...hayflick limit...”
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    Article
  2. 2
    Is There a Positive Side to T Cell Exhaustion?
    by Graham Pawelec, Graham Pawelec
    Published 2019-01-01
    Subjects: “...Hayflick limit...”
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    Article
  3. 3
    A continuum mathematical model of endothelial layer maintenance and senescence
    by Friedman Avner, Aguda Baltazar D, Wang Ying
    Published 2007-08-01
    “... the Hayflick limit of 50 generations is reached, decreasing replication rate parameters and increasing death...”
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    Article
  4. 4
    TINF2 is a haploinsufficient tumor suppressor that limits telomere length
    “... (the Hayflick limit) during tumorigenesis. This model predicts that excessively long somatic telomeres...”
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    Article
  5. 5
    Ring-like distribution of constitutive heterochromatin in bovine senescent cells.
    “...BACKGROUND: Cells that reach "Hayflick limit" of proliferation, known as senescent cells, possess a...”
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    Article
  6. 6
    Labeling of Chromosomes in Cell Development and the Appearance of Monozygotic Twins
    by Carol Jim, Simon Berkovich
    Published 2015-01-01
    “... threshold that is approximately inversely proportional to the Hayflick limit. Exposure to some cancerization...”
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    Article
  7. 7
    Investigation of the Cell Labeling Procedure and the Appearance of Monozygotic Twins
    by Jim, Carol M.
    Published 2015
    “... inversely proportional to the Hayflick limit, so exposure to small levels of ionizing radiation and chemical...”
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  8. 8
    Roles of Telomere Biology in Cell Senescence, Replicative and Chronological Ageing
    by Jun Liu, Lihui Wang, Zhiguo Wang, Jun-Ping Liu
    Published 2019-01-01
    “... cycle arrest at a certain size of telomeres referring to the “Hayflick limit.” In addition...”
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    Article
  9. 9
    A stochastic step model of replicative senescence explains ROS production rate in ageing cell populations.
    “... beyond the Hayflick limit, display high ROS concentrations. We conclude that longitudinal studies...”
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    Article
  10. 10
    Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence.
    “.... IGF-I-treated cells reached the Hayflick limit earlier than GH- or vehicle-treated cells, indicating...”
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    Article
  11. 11
    From zygote to a multicellular soma: Body size affects optimal growth strategies under cancer risk
    by E. Yagmur Erten, Hanna Kokko
    Published 2020-08-01
    “... division), (c) Hayflick limit, (d) damage response threshold, (e) damage response strength, (f) number...”
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    Article
  12. 12
    Telomere dynamics and homeostasis in a transmissible cancer.
    “... for replication, known as the "Hayflick limit".In the present study we investigate the role of telomere length...”
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    Article
  13. 13
    LOSS OF RAB25 COOPERATES WITH ONCOGENES IN THE TRANSFORMATION OF HUMAN MAMMARY EPITHELIAL CELLS (HMEC)
    by Sridhar Joshi, Pooja
    Published 2017
    “... to exceed the Hayflick Limit and become immortal. We have found that with loss of RAB25 and over expression...”
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  14. 14
    Clonal Population of Adult Stem Cells: Life Span and Differentiation Potential
    “... potential of the clonal rMSC line far exceeded Hayflick's limit of 50–70 population doublings. The high...”
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    Article
  15. 15
    Proteome alteration induced by hTERT transfection of human fibroblast cells
    “... telomeres, thereby circumventing the Hayflick limit. Extended-life-span cells have been generated...”
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    Article
  16. 16
    Eco matters; In & Out
    by Editorial
    Published 2016-11-01
    “...]. While the 'Hayflick limit' specifies a particular number of maximum population doubling for a specific...”
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    Article
  17. 17
    Imagerie moléculaire de l’ARN de la télomérase dans des cellules cancéreuses humaines
    by Laprade, Hadrien
    Published 2021
    “... cells. Too short telomeres, reaching the Hayflick limit, will lead the cells to replicative senescence...”
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  18. 18
    Cell Death Pathways and Phthalocyanine as an Efficient Agent for Photodynamic Cancer Therapy
    by Ivan Mfouo-Tynga, Heidi Abrahamse
    Published 2015-05-01
    “... into apoptotic, autophagic and necrotic pathways. The process of Hayflick limits completes the execution of death...”
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    Article
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