Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis

by Özge Karayel, Peng Xu, Isabell Bludau, Senthil Velan Bhoopalan, Yu Yao, Freitas Colaco Ana Rita, Alberto Santos, Brenda A Schulman, Arno F Alpi, Mitchell J Weiss, Matthias Mann
Published 2020-12-01

Side-binding proteins modulate actin filament dynamics

by Alvaro H Crevenna, Marcelino Arciniega, Aurélie Dupont, Naoko Mizuno, Kaja Kowalska, Oliver F Lange, Roland Wedlich-Söldner, Don C Lamb
Published 2015-02-01

Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination Therapy

by Robert Torka, Kinga Pénzes, Simone Gusenbauer, Christine Baumann, István Szabadkai, Lászlȯ Őrfi, György Kéri, Axel Ullrich
Published 2014-04-01

αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin

by Mitasha Bharadwaj, Nico Strohmeyer, Georgina P. Colo, Jonne Helenius, Niko Beerenwinkel, Herbert B. Schiller, Reinhard Fässler, Daniel J. Müller
Published 2017-01-01

Urinary proteome profiling for stratifying patients with familial Parkinson’s disease

by Sebastian Virreira Winter, Ozge Karayel, Maximilian T Strauss, Shalini Padmanabhan, Matthew Surface, Kalpana Merchant, Roy N Alcalay, Matthias Mann
Published 2021-03-01

Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity

by Lukas M Langer, Yair Gat, Fabien Bonneau, Elena Conti
Published 2020-05-01

Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status

by F. Coscia, K. M. Watters, M. Curtis, M. A. Eckert, C. Y. Chiang, S. Tyanova, A. Montag, R. R. Lastra, E. Lengyel, M. Mann
Published 2016-08-01

Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry

by Alexander Reim, Roland Ackermann, Jofre Font-Mateu, Robert Kammel, Miguel Beato, Stefan Nolte, Matthias Mann, Christoph Russmann, Michael Wierer
Published 2020-06-01

Multiplex flow magnetic tweezers reveal rare enzymatic events with single molecule precision

by Rohit Agarwal, Karl E. Duderstadt
Published 2020-09-01

Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease

by Jakob M Bader, Philipp E Geyer, Johannes B Müller, Maximilian T Strauss, Manja Koch, Frank Leypoldt, Peter Koertvelyessy, Daniel Bittner, Carola G Schipke, Enise I Incesoy, Oliver Peters, Nikolaus Deigendesch, Mikael Simons, Majken K Jensen, Henrik Zetterberg, Matthias Mann
Published 2020-06-01

Environmental arginine controls multinuclear giant cell metabolism and formation

by Julia S. Brunner, Loan Vulliard, Melanie Hofmann, Markus Kieler, Alexander Lercher, Andrea Vogel, Marion Russier, Johanna B. Brüggenthies, Martina Kerndl, Victoria Saferding, Birgit Niederreiter, Alexandra Junza, Annika Frauenstein, Carina Scholtysek, Yohei Mikami, Kristaps Klavins, Gerhard Krönke, Andreas Bergthaler, John J. O’Shea, Thomas Weichhart, Felix Meissner, Josef S. Smolen, Paul Cheng, Oscar Yanes, Jörg Menche, Peter J. Murray, Omar Sharif, Stephan Blüml, Gernot Schabbauer
Published 2020-01-01

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

by Martin Steger, Francesca Tonelli, Genta Ito, Paul Davies, Matthias Trost, Melanie Vetter, Stefanie Wachter, Esben Lorentzen, Graham Duddy, Stephen Wilson, Marco AS Baptista, Brian K Fiske, Matthew J Fell, John A Morrow, Alastair D Reith, Dario R Alessi, Matthias Mann
Published 2016-01-01

AnnoMiner is a new web-tool to integrate epigenetics, transcription factor occupancy and transcriptomics data to predict transcriptional regulators

by Arno Meiler, Fabio Marchiano, Margaux Haering, Manuela Weitkunat, Frank Schnorrer, Bianca H. Habermann
Published 2021-07-01

Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

by Michal Bassani-Sternberg, Eva Bräunlein, Richard Klar, Thomas Engleitner, Pavel Sinitcyn, Stefan Audehm, Melanie Straub, Julia Weber, Julia Slotta-Huspenina, Katja Specht, Marc E. Martignoni, Angelika Werner, Rüdiger Hein, Dirk H. Busch, Christian Peschel, Roland Rad, Jürgen Cox, Matthias Mann, Angela M. Krackhardt
Published 2016-11-01

Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients

by Zhiguang Xiao, Silvia Gaertner, Alicia Morresi-Hauf, Rebecca Genzel, Thomas Duell, Axel Ullrich, Pjotr G. Knyazev
Published 2017-05-01

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model

by Frédéric Frottin, Manuela Pérez-Berlanga, F Ulrich Hartl, Mark S Hipp
Published 2021-06-01

A Mass Spectrometry-Based Approach for Mapping Protein Subcellular Localization Reveals the Spatial Proteome of Mouse Primary Neurons

by Daniel N. Itzhak, Colin Davies, Stefka Tyanova, Archana Mishra, James Williamson, Robin Antrobus, Jürgen Cox, Michael P. Weekes, Georg H.H. Borner
Published 2017-09-01

Quantitative sensing and signalling of single-stranded DNA during the DNA damage response

by Susanne C. S. Bantele, Michael Lisby, Boris Pfander
Published 2019-02-01

Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness

by Leo E. Wong, Arshiya Bhatt, Philipp S. Erdmann, Zhen Hou, Joachim Maier, Sona Pirkuliyeva, Michael Engelke, Stefan Becker, Jürgen Plitzko, Jürgen Wienands, Christian Griesinger
Published 2020-02-01

Determining the bacterial cell biology of Planctomycetes

by Christian Boedeker, Margarete Schüler, Greta Reintjes, Olga Jeske, Muriel C. F. van Teeseling, Mareike Jogler, Patrick Rast, Daniela Borchert, Damien P. Devos, Martin Kucklick, Miroslava Schaffer, Roberto Kolter, Laura van Niftrik, Susanne Engelmann, Rudolf Amann, Manfred Rohde, Harald Engelhardt, Christian Jogler
Published 2017-04-01