β-Funaltrexamine Displayed Anti-inflammatory and Neuroprotective Effects in Cells and Rat Model of Stroke

by Chih-Cheng Wu, Cheng-Yi Chang, Kuei-Chung Shih, Chih-Jen Hung, Ya-Yu Wang, Shih-Yi Lin, Wen-Ying Chen, Yu-Hsiang Kuan, Su-Lan Liao, Wen-Yi Wang, Chun-Jung Chen
Published 2020-05-01

Effects of β-Adrenergic Blockade on Metabolic and Inflammatory Responses in a Rat Model of Ischemic Stroke

by Shih-Yi Lin, Ya-Yu Wang, Cheng-Yi Chang, Chih-Cheng Wu, Wen-Ying Chen, Yu-Hsiang Kuan, Su-Lan Liao, Chun-Jung Chen
Published 2020-06-01

Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures

by Bei Zhang, Yi-Zheng Wei, Guo-Qing Wang, Dai-Di Li, Jing-Shan Shi, Feng Zhang
Published 2019-01-01

A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration

by Meng-meng Jin, Meng-meng Jin, Meng-meng Jin, Fen Wang, Di Qi, Wen-wen Liu, Chao Gu, Chao Gu, Cheng-Jie Mao, Ya-Ping Yang, Zhong Zhao, Li-Fang Hu, Li-Fang Hu, Chun-Feng Liu, Chun-Feng Liu, Chun-Feng Liu
Published 2018-11-01

Influence of Estrogen Modulation on Glia Activation in a Murine Model of Parkinson's Disease

by Francesca Siani, Rosaria Greco, Giovanna Levandis, Cristina Ghezzi, Francesca Daviddi, Chiara Demartini, Elisabetta Vegeto, Marie-Thérèse Fuzzati-Armentero, Fabio Blandini
Published 2017-05-01

A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation

by Sha Liao, Jingni Wu, Ruimin Liu, Shixiang Wang, Jing Luo, Yang Yang, Yannan Qin, Tao Li, Xiaopu Zheng, Jing Song, Xinfeng Zhao, Chaoni Xiao, Yajun Zhang, Liujiao Bian, Pu Jia, Yajun Bai, Xiaohui Zheng
Published 2020-09-01

Astragaloside IV protects neurons from microglia-mediated cell damage through promoting microglia polarization

by Jingwen Yu, Minfang Guo, Yanhua Li, Huiyu Zhang, Zhi Chai, Qing Wang, Yuqing Yan, Jiezhong Yu, Chunyun Liu, Guangxian Zhang, Ma Cungen
Published 2019-06-01

Alpha-1 Antitrypsin Attenuates M1 Microglia-Mediated Neuroinflammation in Retinal Degeneration

by Tian Zhou, Zijing Huang, Xiaowei Zhu, Xiaowei Sun, Yan Liu, Bing Cheng, Mei Li, Yizhi Liu, Chang He, Xialin Liu
Published 2018-05-01

The Role of Alpha-Lipoic Acid in the Pathomechanism of Acute Ischemic Stroke

by Qingqing Wang, Chengmei Lv, Yongxin Sun, Xu Han, Shan Wang, Zhengchun Mao, Yanming Xin, Bing Zhang
Published 2018-07-01

Camptothecin Regulates Microglia Polarization and Exerts Neuroprotective Effects via Activating AKT/Nrf2/HO-1 and Inhibiting NF-κB Pathways In Vivo and In Vitro

by Dewei He, Shoupeng Fu, Ang Zhou, Yingchun Su, Xiyu Gao, Yufei Zhang, Bingxu Huang, Jian Du, Dianfeng Liu
Published 2021-04-01

An antarctic krill oil-based diet elicits neuroprotective effects by inhibiting oxidative stress and rebalancing the M1/M2 microglia phenotype in a cuprizone model for demyelinatio...

by Ning Zhang, Li Jin, Chunhong Liu, Ruiyan Zhang, Hans-Christian Siebert, Yanhui Li, Gabriele Loers, Athanasios K. Petridis, Zhangyong Xia, Huijun Dong, Xuexing Zheng
Published 2021-01-01

Tamoxifen suppresses brain metastasis of estrogen receptor-deficient breast cancer by skewing microglia polarization and enhancing their immune functions

by Shih-Ying Wu, Sambad Sharma, Kerui Wu, Abhishek Tyagi, Dan Zhao, Ravindra Pramod Deshpande, Kounosuke Watabe
Published 2021-03-01

Curcumin Mitigates Neuro-Inflammation by Modulating Microglia Polarization Through Inhibiting TLR4 Axis Signaling Pathway Following Experimental Subarachnoid Hemorrhage

by YongYue Gao, Zong Zhuang, Yue Lu, Tao Tao, Yan Zhou, GuangJie Liu, Han Wang, DingDing Zhang, LingYun Wu, HaiBin Dai, Wei Li, ChunHua Hang
Published 2019-11-01

Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis

by Bingrun Liu, Bingrun Liu, Bingxu Huang, Guiqiu Hu, Dewei He, Yuhang Li, Xin Ran, Jian Du, Shoupeng Fu, Dianfeng Liu
Published 2019-11-01

Corrigendum: Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis

by Bingrun Liu, Bingrun Liu, Bingxu Huang, Guiqiu Hu, Dewei He, Yuhang Li, Xin Ran, Jian Du, Shoupeng Fu, Dianfeng Liu
Published 2020-01-01

LncRNA HOXA-AS2 regulates microglial polarization via recruitment of PRC2 and epigenetic modification of PGC-1α expression

by Xiaodong Yang, Yi Zhang, Yimeng Chen, Xiaoqin He, Yiwei Qian, Shaoqing Xu, Chao Gao, Chengjun Mo, Shengdi Chen, Qin Xiao
Published 2021-09-01

Soluble epoxide hydrolase inhibition enhances anti-inflammatory and antioxidative processes, modulates microglia polarization, and promotes recovery after ischemic stroke

by Yeh CF, Chuang TY, Hung YW, Lan MY, Tsai CH, Huang HX, Lin YY
Published 2019-10-01

Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKKβ-Dependent AMPK Activation

by Chuwen Li, Chao Zhang, Chao Zhang, Hefeng Zhou, Yu Feng, Fan Tang, Maggie P. M. Hoi, Chengwei He, Dan Ma, Chao Zhao, Simon M. Y. Lee
Published 2018-04-01

CISD2 Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells—As a Potential Therapeutic Target for Neurodegenerative Dementia

by Muh-Shi Lin, Muh-Shi Lin, Muh-Shi Lin, Muh-Shi Lin
Published 2020-08-01