Function-triggering antibodies to the adhesion molecule L1 enhance recovery after injury of the adult mouse femoral nerve.

by Daria Guseva, Gabriele Loers, Melitta Schachner
Published 2014-01-01

Proteins Binding to the Carbohydrate HNK-1: Common Origins?

by Gaston Castillo, Ralf Kleene, Melitta Schachner, Gabriele Loers, Andrew E. Torda
Published 2021-07-01

Generation and intracellular trafficking of a polysialic acid-carrying fragment of the neural cell adhesion molecule NCAM to the cell nucleus

by Nina Westphal, Gabriele Loers, David Lutz, Thomas Theis, Ralf Kleene, Melitta Schachner
Published 2017-08-01

Functions of Small Organic Compounds that Mimic the HNK-1 Glycan

by Minjuan Wang, Thomas Theis, Maciej Kabat, Gabriele Loers, Lynn A. Agre, Melitta Schachner
Published 2020-09-01

Generation of amyloid-β is reduced by the interaction of calreticulin with amyloid precursor protein, presenilin and nicastrin.

by Nina Stemmer, Elena Strekalova, Nevena Djogo, Frank Plöger, Gabriele Loers, David Lutz, Friedrich Buck, Marek Michalak, Melitta Schachner, Ralf Kleene
Published 2013-01-01

Adhesion molecule L1 binds to amyloid beta and reduces Alzheimer's disease pathology in mice

by Nevena Djogo, Igor Jakovcevski, Christian Müller, Hyun Joon Lee, Jin-Chong Xu, Mira Jakovcevski, Sebastian Kügler, Gabriele Loers, Melitta Schachner
Published 2013-08-01

Antibody fragments directed against different portions of the human neural cell adhesion molecule L1 act as inhibitors or activators of L1 function.

by Yan Wang, Gabriele Loers, Hong-Chao Pan, Ricardo Gouveia, Wei-Jiang Zhao, Yan-Qin Shen, Ralf Kleene, Julia Costa, Melitta Schachner
Published 2012-01-01

Cell surface sialylation and fucosylation are regulated by L1 via phospholipase Cgamma and cooperate to modulate neurite outgrowth, cell survival and migration.

by Ya-Li Li, Guang-Zhi Wu, Gavin S Dawe, Li Zeng, Shu-Sen Cui, Gabriele Loers, Thomas Tilling, Li Sun, Melitta Schachner, Zhi-Cheng Xiao
Published 2008-01-01

An antarctic krill oil-based diet elicits neuroprotective effects by inhibiting oxidative stress and rebalancing the M1/M2 microglia phenotype in a cuprizone model for demyelinatio...

by Ning Zhang, Li Jin, Chunhong Liu, Ruiyan Zhang, Hans-Christian Siebert, Yanhui Li, Gabriele Loers, Athanasios K. Petridis, Zhangyong Xia, Huijun Dong, Xuexing Zheng
Published 2021-01-01