Long-Term Assessment of AAV-Mediated Zinc Finger Nuclease Expression in the Mouse Brain

by Muzna Zahur, Johan Tolö, Johan Tolö, Mathias Bähr, Mathias Bähr, Sebastian Kügler, Sebastian Kügler
Published 2017-05-01

Patterning inconsistencies restrict the true potential of dopaminergic neurons derived from human induced pluripotent stem cells

by Sameehan Mahajani, Mathias Bähr, Sebastian Kügler
Published 2021-01-01

A MicroRNA124 Target Sequence Restores Astrocyte Specificity of gfaABC1D-Driven Transgene Expression in AAV-Mediated Gene Transfer

by Grit Taschenberger, Julia Tereshchenko, Sebastian Kügler
Published 2017-09-01

Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease

by Tomasz Jaworski, Sebastian Kügler, Fred Van Leuven
Published 2010-01-01

Overshooting Subcellular Redox-Responses in Rett-Mouse Hippocampus during Neurotransmitter Stimulation

by Karina Festerling, Karolina Can, Sebastian Kügler, Michael Müller
Published 2020-11-01

Adeno-associated Virus-mediated, Mifepristone-regulated Transgene Expression in the Brain

by Andrea Maddalena, Julia Tereshchenko, Mathias Bähr, Sebastian Kügler
Published 2013-01-01

Pharmacologically controlled, discontinuous GDNF gene therapy restores motor function in a rat model of Parkinson's disease

by Julia Tereshchenko, Andrea Maddalena, Mathias Bähr, Sebastian Kügler
Published 2014-05-01

Adenovirus-Mediated Glial Cell Line-Derived Neurotrophic Factor (GDNF) Expression Protects against Subsequent Cortical Cold Injury in Rats

by Dirk M. Hermann, Ertugrul Kilic, Sebastian Kügler, Stefan Isenmann, Mathias Bähr
Published 2001-12-01

Adenovirus-Mediated GDNF and CNTF Pretreatment Protects against Striatal Injury Following Transient Middle Cerebral Artery Occlusion in Mice

by Dirk M. Hermann, Ertugrul Kilic, Sebastian Kügler, Stefan Isenmann, Mathias Bähr
Published 2001-08-01

Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O2 Consumption and ROS Release

by Karolina Can, Karolina Can, Christiane Menzfeld, Christiane Menzfeld, Lena Rinne, Peter Rehling, Sebastian Kügler, Sebastian Kügler, Gocha Golubiani, Gocha Golubiani, Jan Dudek, Michael Müller, Michael Müller
Published 2019-04-01

CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies

by Sara Castro-Sánchez, Ángel J. García-Yagüe, Sebastian Kügler, Isabel Lastres-Becker
Published 2019-04-01

Overexpression of BDNF increases excitability of the lumbar spinal network and leads to robust early locomotor recovery in completely spinalized rats.

by Ewelina Ziemlińska, Sebastian Kügler, Melitta Schachner, Iwona Wewiór, Julita Czarkowska-Bauch, Małgorzata Skup
Published 2014-01-01

Optimized pharmacological control over the AAV-Gene-Switch vector for regulable gene therapy

by Shi Cheng, Marcel M. van Gaalen, Mathias Bähr, Enrique Garea-Rodriguez, Sebastian Kügler
Published 2021-12-01

Adenovirus-Mediated Expression of Ciliary Neurotrophic Factor (CNTF) Rescues Axotomized Rat Retinal Ganglion Cells But Does Not Support Axonal Regeneration in Vivo

by Jens Weise, Stefan Isenmann, Nikolaj Klöcker, Sebastian Kügler, Sabine Hirsch, Claude Gravel, Mathias Bähr
Published 2000-06-01

A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice

by Hanan Al‐Moyed, Andreia P Cepeda, SangYong Jung, Tobias Moser, Sebastian Kügler, Ellen Reisinger
Published 2019-01-01

Adenovirus-Mediated Bcl-XL Expression Using a Neuron-Specific Synapsin-1 Promoter Protects against Disseminated Neuronal Injury and Brain Infarction Following Focal Cerebral Ischem...

by Ertugrul Kilic, Dirk M. Hermann, Sebastian Kügler, ;Ülkan Kilic, Harry Holzmüller, Christian Schmeer, Mathias Bähr
Published 2002-11-01

Neuronal expression of the human neuropeptide S receptor NPSR1 identifies NPS-induced calcium signaling pathways.

by Frank Erdmann, Sebastian Kügler, Peter Blaesse, Maren D Lange, Boris V Skryabin, Hans-Christian Pape, Kay Jüngling
Published 2015-01-01

Potential Synergistic Protection of Retinal Ganglion Cells from Axotomy-Induced Apoptosis by Adenoviral Administration of Glial Cell Line-Derived Neurotrophic Factor and X-Chromoso...

by Guido Straten, Christian Schmeer, Alexandra Kretz, Ellen Gerhardt, Sebastian Kügler, Jörg B. Schulz, Claude Gravel, Mathias Bähr, Stefan Isenmann
Published 2002-10-01

Pathophysiological Consequences of Neuronal α-Synuclein Overexpression: Impacts on Ion Homeostasis, Stress Signaling, Mitochondrial Integrity, and Electrical Activity

by Johan Tolö, Grit Taschenberger, Grit Taschenberger, Kristian Leite, Markus A. Stahlberg, Gesche Spehlbrink, Janina Kues, Francesca Munari, Francesca Munari, Stefano Capaldi, Stefan Becker, Markus Zweckstetter, Markus Zweckstetter, Markus Zweckstetter, Markus Zweckstetter, Camin Dean, Camin Dean, Mathias Bähr, Mathias Bähr, Sebastian Kügler, Sebastian Kügler
Published 2018-03-01

Adhesion molecule L1 binds to amyloid beta and reduces Alzheimer's disease pathology in mice

by Nevena Djogo, Igor Jakovcevski, Christian Müller, Hyun Joon Lee, Jin-Chong Xu, Mira Jakovcevski, Sebastian Kügler, Gabriele Loers, Melitta Schachner
Published 2013-08-01