Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients

by Takeshi Tokuyama, Asei Hirai, Isshin Shiiba, Naoki Ito, Keigo Matsuno, Keisuke Takeda, Kanata Saito, Koki Mii, Nobuko Matsushita, Toshifumi Fukuda, Ryoko Inatome, Shigeru Yanagi
Published 2020-03-01

p47Phox/CDK5/DRP1-Mediated Mitochondrial Fission Evokes PV Cell Degeneration in the Rat Dentate Gyrus Following Status Epilepticus

by Ji-Eun Kim, Tae-Cheon Kang
Published 2017-09-01

Zika Virus-Induced Neuronal Apoptosis via Increased Mitochondrial Fragmentation

by Shu Yang, Kirill Gorshkov, Emily M. Lee, Miao Xu, Yu-Shan Cheng, Nuo Sun, Ferri Soheilian, Natalia de Val, Guoli Ming, Hongjun Song, Hengli Tang, Wei Zheng
Published 2020-12-01

Metformin alleviates lead-induced mitochondrial fragmentation via AMPK/Nrf2 activation in SH-SY5Y cells

by Luoyao Yang, Xiaoyi Li, Anli Jiang, Xintong Li, Wei Chang, Jun Chen, Fang Ye
Published 2020-09-01

Mitochondrial Fragmentation and Dysfunction in Type IIx/IIb Diaphragm Muscle Fibers in 24-Month Old Fischer 344 Rats

by Alyssa D. Brown, Leah A. Davis, Matthew J. Fogarty, Gary C. Sieck
Published 2021-09-01

Nicotinamide Treatment Facilitates Mitochondrial Fission through Drp1 Activation Mediated by SIRT1-Induced Changes in Cellular Levels of cAMP and Ca²⁺

by Seon Beom Song, Jin Sung Park, So Young Jang, Eun Seong Hwang
Published 2021-03-01

A novel AFG3L2 mutation close to AAA domain leads to aberrant OMA1 and OPA1 processing in a family with optic atrophy

by Valentina Baderna, Joshua Schultz, Lisa S. Kearns, Michael Fahey, Bryony A. Thompson, Jonathan B. Ruddle, Aamira Huq, Francesca Maltecca
Published 2020-06-01

Cyclooxygenase-2-Mediated Up-Regulation of Mitochondrial Transcription Factor A Mitigates the Radio-Sensitivity of Cancer Cells

by Fan Tang, Rui Zhang, Jun Wang
Published 2019-03-01

Propagation of Mitochondria-Derived Reactive Oxygen Species within the <i>Dipodascus magnusii</i> Cells

by Anton G. Rogov, Tatiana N. Goleva, Khoren K. Epremyan, Igor I. Kireev, Renata A. Zvyagilskaya
Published 2021-01-01

Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation

by Alan Diot, Thomas Agnew, Jeremy Sanderson, Chunyan Liao, Janet Carver, Ricardo Pires das Neves, Rajeev Gupta, Yanping Guo, Caroline Waters, Sharon Seto, Matthew J. Daniels, Eszter Dombi, Tiffany Lodge, Karl Morten, Suzannah A. Williams, Tariq Enver, Francisco J. Iborra, Marcela Votruba, Joanna Poulton
Published 2018-09-01

Excessive mitochondrial fragmentation triggered by erlotinib promotes pancreatic cancer PANC-1 cell apoptosis via activating the mROS-HtrA2/Omi pathways

by Jun Wan, Jie Cui, Lei Wang, Kunpeng Wu, Xiaoping Hong, Yulin Zou, Shuang Zhao, Hong Ke
Published 2018-10-01

Mitofusin 1 is degraded at G₂/M phase through ubiquitylation by MARCH5

by Park Yong-Yea, Cho Hyeseong
Published 2012-12-01

Hyperglycaemia Stress-Induced Renal Injury is Caused by Extensive Mitochondrial Fragmentation, Attenuated MKP1 Signalling, and Activated JNK-CaMKII-Fis1 Biological Axis

by Yunfang Zhang, Junxia Feng, Qi Wang, Shili Zhao, Shen Yang, Lu Tian, Ping Meng, Jingchun Li, Hongyan Li
Published 2018-11-01

Silencing of Poly(ADP-Ribose) Polymerase-2 Induces Mitochondrial Reactive Species Production and Mitochondrial Fragmentation

by Laura Jankó, Tünde Kovács, Miklós Laczik, Zsanett Sári, Gyula Ujlaki, Gréta Kis, Ibolya Horváth, Miklós Antal, László Vígh, Bálint L. Bálint, Karen Uray, Péter Bai
Published 2021-06-01

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

by Bianca Hartmann, Timothy Wai, Hao Hu, Thomas MacVicar, Luciana Musante, Björn Fischer-Zirnsak, Werner Stenzel, Ralph Gräf, Lambert van den Heuvel, Hans-Hilger Ropers, Thomas F Wienker, Christoph Hübner, Thomas Langer, Angela M Kaindl
Published 2016-08-01

Mst1-Hippo pathway triggers breast cancer apoptosis via inducing mitochondrial fragmentation in a manner dependent on JNK&ndash;Drp1 axis

by Ouyang H, Zhou E, Wang H
Published 2019-02-01

Drp1‐dependent peptide reverse mitochondrial fragmentation, a homeostatic response in Friedreich ataxia

by Joseph Johnson, Elizabeth Mercado‐Ayón, Elisia Clark, David Lynch, Hong Lin
Published 2021-05-01

The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis

by Joshua A. Grosser, Rachel L. Fehrman, Dennis Keefe, Martin Redmon, Robert W. Nickells
Published 2021-05-01

Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death

by Song Han, Priya Nandy, Quillan Austria, Sandra L. Siedlak, Sandy Torres, Hisashi Fujioka, Wenzhang Wang, Xiongwei Zhu
Published 2020-01-01

Hepatic Knockdown of Endothelin Type A Receptor (ETAR) Ameliorates Hepatic Insulin Resistance and Hyperglycemia Through Suppressing p66Shc-Mediated Mitochondrial Fragmentation in H...

by Feng L, Wang S, Chen F, Zhang C, Wang Q, Zhao Y, Zhang Z
Published 2021-03-01