Frontiers in Molecular Neuroscience – Résumé and Perspective

by Jochen C Meier, Robert J Harvey, Peter H Seeburg
Published 2011-12-01

Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features

by Jon M. Madison, Karen Duong, Ellen F. Vieux, Namrata D. Udeshi, Sumaiya Iqbal, Elise Requadt, Shaunt Fereshetian, Michael C. Lewis, Antonio S. Gomes, Kerry A. Pierce, Randall J. Platt, Feng Zhang, Arthur J. Campbell, Dennis Lal, Florence F. Wagner, Clary B. Clish, Steven A. Carr, Morgan Sheng, Edward M. Scolnick, Jeffrey R. Cottrell
Published 2021-01-01

Moderate Changes in CO2 Modulate the Firing of Neurons in the VTA and Substantia Nigra

by Emily Hill, Nicholas Dale, Mark J. Wall
Published 2020-07-01

Sustained postsynaptic kainate receptor activation downregulates AMPA receptor surface expression and induces hippocampal LTD

by Jithin D. Nair, Ellen Braksator, Busra P. Yucel, Alexandra Fletcher-Jones, Richard Seager, Jack R. Mellor, Zafar I. Bashir, Kevin A. Wilkinson, Jeremy M. Henley
Published 2021-09-01

Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease

by Jorge A. Aguilar-Pineda, Karin J. Vera-Lopez, Pallavi Shrivastava, Miguel A. Chávez-Fumagalli, Rita Nieto-Montesinos, Karla L. Alvarez-Fernandez, Luis D. Goyzueta Mamani, Gonzalo Davila Del-Carpio, Badhin Gomez-Valdez, Clint L. Miller, Rajeev Malhotra, Mark E. Lindsay, Christian L. Lino Cardenas
Published 2021-09-01

TLR7 and IL-6 differentially regulate the effects of rotarod exercise on the transcriptomic profile and neurogenesis to influence anxiety and memory

by Yun-Fen Hung, Yi-Ping Hsueh
Published 2021-04-01

ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function

by Takashi Sugiyama, Naoya Murao, Hisae Kadowaki, Keizo Takao, Tsuyoshi Miyakawa, Yosuke Matsushita, Toyomasa Katagiri, Akira Futatsugi, Yohei Shinmyo, Hiroshi Kawasaki, Juro Sakai, Kazutaka Shiomi, Masamitsu Nakazato, Kohsuke Takeda, Katsuhiko Mikoshiba, Hidde L. Ploegh, Hidenori Ichijo, Hideki Nishitoh
Published 2021-07-01

Perturbed DNA methylation by Gadd45b induces chromatin disorganization, DNA strand breaks and dopaminergic neuron death

by Camille Ravel-Godreuil, Olivia Massiani-Beaudoin, Philippe Mailly, Alain Prochiantz, Rajiv L. Joshi, Julia Fuchs
Published 2021-07-01

The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments

by Sylwia Król, Nicklas Österlund, Faraz Vosough, Jüri Jarvet, Sebastian Wärmländer, Andreas Barth, Leopold L. Ilag, Mazin Magzoub, Astrid Gräslund, Cecilia Mörman
Published 2021-08-01

Structural basis for SARM1 inhibition and activation under energetic stress

by Michael Sporny, Julia Guez-Haddad, Tami Khazma, Avraham Yaron, Moshe Dessau, Yoel Shkolnisky, Carsten Mim, Michail N Isupov, Ran Zalk, Michael Hons, Yarden Opatowsky
Published 2020-11-01

Metal- and UV- Catalyzed Oxidation Results in Trapped Amyloid-β Intermediates Revealing that Self-Assembly Is Required for Aβ-Induced Cytotoxicity

by Mahmoud B. Maina, Gunasekhar Burra, Youssra K. Al-Hilaly, Kurtis Mengham, Kate Fennell, Louise C. Serpell
Published 2020-10-01

Molecular Crowding and Diffusion-Capture in Synapses

by Marianna Lamprou Kokolaki, Aurélien Fauquier, Marianne Renner
Published 2020-08-01

Skeletal-Muscle Metabolic Reprogramming in ALS-SOD1G93A Mice Predates Disease Onset and Is A Promising Therapeutic Target

by Silvia Scaricamazza, Illari Salvatori, Giacomo Giacovazzo, Jean Philippe Loeffler, Frederique Renè, Marco Rosina, Cyril Quessada, Daisy Proietti, Constantin Heil, Simona Rossi, Stefania Battistini, Fabio Giannini, Nila Volpi, Frederik J. Steyn, Shyuan T. Ngo, Elisabetta Ferraro, Luca Madaro, Roberto Coccurello, Cristiana Valle, Alberto Ferri
Published 2020-05-01

The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging

by Connor M. Wander, Jui-Heng Tseng, Sheng Song, Heba A. Al Housseiny, Dalton S. Tart, Aditi Ajit, Yen-Yu Ian Shih, Rebecca Lobrovich, Juan Song, Rick B. Meeker, David J. Irwin, Todd J. Cohen
Published 2020-07-01

Glycogenolysis Is Crucial for Astrocytic Glycogen Accumulation and Brain Damage after Reperfusion in Ischemic Stroke

by Yanhui Cai, Haiyun Guo, Ze Fan, Xinlei Zhang, Di Wu, Wenhong Tang, Tingting Gu, Shiquan Wang, Anqi Yin, Liang Tao, Xunming Ji, Hailong Dong, Yan Li, Lize Xiong
Published 2020-05-01

Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons

by Rohit Kumar, Sainitin Donakonda, Stephan A. Müller, Stefan F. Lichtenthaler, Kai Bötzel, Günter U. Höglinger, Thomas Koeglsperger
Published 2020-08-01

Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism

by Arielle N. Valdez-Sinon, Austin Lai, Liang Shi, Carly L. Lancaster, Avanti Gokhale, Victor Faundez, Gary J. Bassell
Published 2020-05-01

The Dichotomous Role of Extracellular Vesicles in the Central Nervous System

by David R. Graykowski, Yi-Zhi Wang, Arun Upadhyay, Jeffrey N. Savas
Published 2020-09-01

Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission

by Jenny M. Brown, Marie A. Bentsen, Dylan M. Rausch, Bao Anh Phan, Danielle Wieck, Huzaifa Wasanwala, Miles E. Matsen, Nikhil Acharya, Nicole E. Richardson, Xin Zhao, Peng Zhai, Anna Secher, Gregory J. Morton, Tune H. Pers, Michael W. Schwartz, Jarrad M. Scarlett
Published 2021-09-01

Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels

by Haritha P. Reddy, Daniel Yakubovich, Tal Keren-Raifman, Galit Tabak, Vladimir A. Tsemakhovich, Maria H. Pedersen, Boris Shalomov, Sophie Colombo, David B. Goldstein, Jonathan A. Javitch, Amal K. Bera, Nathan Dascal
Published 2021-09-01