Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders

by Yi-Zhi Wang, Jeffrey N. Savas
Published 2018-07-01

The Dichotomous Role of Extracellular Vesicles in the Central Nervous System

by David R. Graykowski, Yi-Zhi Wang, Arun Upadhyay, Jeffrey N. Savas
Published 2020-09-01

Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry

by Pan Liu, Seby Louis Edassery, Laith Ali, Benjamin R Thomson, Jeffrey N Savas, Jing Jin
Published 2019-12-01

Analysis of URI nuclear interaction with RPB5 and components of the R2TP/prefoldin-like complex.

by Paolo Mita, Jeffrey N Savas, Susan Ha, Nabil Djouder, John R Yates, Susan K Logan
Published 2013-01-01

Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function.

by Jean J Kim, Jeffrey N Savas, Meghan T Miller, Xindao Hu, Cassiano Carromeu, Mathieu Lavallée-Adam, Beatriz C G Freitas, Alysson R Muotri, John R Yates, Anirvan Ghosh
Published 2019-01-01

Differences in AMPA and Kainate Receptor Interactomes Facilitate Identification of AMPA Receptor Auxiliary Subunit GSG1L

by Natalie F. Shanks, Jeffrey N. Savas, Tomohiko Maruo, Ondrej Cais, Atsushi Hirao, Souichi Oe, Anirvan Ghosh, Yasuko Noda, Ingo H. Greger, John R. Yates, III, Terunaga Nakagawa
Published 2012-06-01

Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer

by Nuno Apóstolo, Samuel N. Smukowski, Jeroen Vanderlinden, Giuseppe Condomitti, Vasily Rybakin, Jolijn ten Bos, Laura Trobiani, Sybren Portegies, Kristel M. Vennekens, Natalia V. Gounko, Davide Comoletti, Keimpe D. Wierda, Jeffrey N. Savas, Joris de Wit
Published 2020-10-01

Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function

by Matthew Wortham, Jacqueline R. Benthuysen, Martina Wallace, Jeffrey N. Savas, Francesca Mulas, Ajit S. Divakaruni, Fenfen Liu, Verena Albert, Brandon L. Taylor, Yinghui Sui, Enrique Saez, Anne N. Murphy, John R. Yates, III, Christian M. Metallo, Maike Sander
Published 2018-12-01

The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation

by Ryo Yonashiro, Erich B Tahara, Mario H Bengtson, Maria Khokhrina, Holger Lorenz, Kai-Chun Chen, Yu Kigoshi-Tansho, Jeffrey N Savas, John R Yates III, Steve A Kay, Elizabeth A Craig, Axel Mogk, Bernd Bukau, Claudio AP Joazeiro
Published 2016-03-01

Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways

by David A. Ruhl, Ewa Bomba-Warczak, Emma T. Watson, Mazdak M. Bradberry, Tabitha A. Peterson, Trina Basu, Alyssa Frelka, Chantell S. Evans, Joseph S. Briguglio, Tamara Basta, Michael H. B. Stowell, Jeffrey N. Savas, Avtar Roopra, Robert A. Pearce, Robert C. Piper, Edwin R. Chapman
Published 2019-08-01

Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer’s Disease-like Pathology

by Jeffrey N. Savas, Yi-Zhi Wang, Laura A. DeNardo, Salvador Martinez-Bartolome, Daniel B. McClatchy, Timothy J. Hark, Natalie F. Shanks, Kira A. Cozzolino, Mathieu Lavallée-Adam, Samuel N. Smukowski, Sung Kyu Park, Jeffery W. Kelly, Edward H. Koo, Terunaga Nakagawa, Eliezer Masliah, Anirvan Ghosh, John R. Yates, III
Published 2017-11-01