Brain organoids and insights on human evolution [version 1; peer review: 4 approved]

by Alysson R. Muotri
Published 2019-05-01

Editorial: Brain Organoids: Modeling in Neuroscience

by Matteo Bordoni, Alysson R. Muotri, Alysson R. Muotri, Cristina Cereda
Published 2020-10-01

Transposable Elements, Inflammation, and Neurological Disease

by Aurian Saleh, Angela Macia, Alysson R. Muotri
Published 2019-08-01

All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors

by Francesca Puppo, Sanaz Sadegh, Cleber A. Trujillo, Cleber A. Trujillo, Martin Thunemann, Evan P. Campbell, Matthieu Vandenberghe, Xiwei Shan, Xiwei Shan, Ibrahim A. Akkouh, Evan W. Miller, Brenda L. Bloodgood, Gabriel A. Silva, Anders M. Dale, Gaute T. Einevoll, Gaute T. Einevoll, Srdjan Djurovic, Srdjan Djurovic, Ole A. Andreassen, Alysson R. Muotri, Alysson R. Muotri, Alysson R. Muotri, Alysson R. Muotri, Anna Devor, Anna Devor
Published 2021-05-01

Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids

by Ana Rita Gomes, Ana Rita Gomes, Tiago G. Fernandes, Sandra H. Vaz, Sandra H. Vaz, Teresa P. Silva, Teresa P. Silva, Evguenia P. Bekman, Evguenia P. Bekman, Evguenia P. Bekman, Sara Xapelli, Sara Xapelli, Sofia Duarte, Mehrnaz Ghazvini, Joost Gribnau, Alysson R. Muotri, Alysson R. Muotri, Alysson R. Muotri, Alysson R. Muotri, Alysson R. Muotri, Cleber A. Trujillo, Cleber A. Trujillo, Cleber A. Trujillo, Ana M. Sebastião, Ana M. Sebastião, Joaquim M. S. Cabral, Maria Margarida Diogo
Published 2020-12-01

Methadone Suppresses Neuronal Function and Maturation in Human Cortical Organoids

by Wei Wu, Hang Yao, Ila Dwivedi, Priscilla D. Negraes, Helen W. Zhao, Juan Wang, Cleber A. Trujillo, Alysson R. Muotri, Alysson R. Muotri, Gabriel G. Haddad, Gabriel G. Haddad, Gabriel G. Haddad
Published 2020-11-01

Transcription factor 4 and its association with psychiatric disorders

by José R. Teixeira, Ryan A. Szeto, Vinicius M. A. Carvalho, Alysson R. Muotri, Fabio Papes
Published 2021-01-01

Transcriptional signature and memory retention of human-induced pluripotent stem cells.

by Maria C N Marchetto, Gene W Yeo, Osamu Kainohana, Martin Marsala, Fred H Gage, Alysson R Muotri
Published 2009-09-01

Alternative splicing events identified in human embryonic stem cells and neural progenitors.

by Gene W Yeo, Xiangdong Xu, Tiffany Y Liang, Alysson R Muotri, Christian T Carson, Nicole G Coufal, Fred H Gage
Published 2007-10-01

Methadone interrupts neural growth and function in human cortical organoids

by Hang Yao, Wei Wu, Ines Cerf, Helen W. Zhao, Juan Wang, Priscilla D. Negraes, Alysson R. Muotri, Gabriel G. Haddad
Published 2020-12-01

Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function.

by Jean J Kim, Jeffrey N Savas, Meghan T Miller, Xindao Hu, Cassiano Carromeu, Mathieu Lavallée-Adam, Beatriz C G Freitas, Alysson R Muotri, John R Yates, Anirvan Ghosh
Published 2019-01-01

Feeder-Free Derivation of Induced Pluripotent Stem Cells from Human Immature Dental Pulp Stem Cells

by Patrícia C. B. Beltrão-Braga, Graciela C. Pignatari, Paulo C. Maiorka, Nélio A. J. Oliveira, Nelson F. Lizier, Cristiane V. Wenceslau, Maria A. Miglino, Alysson R. Muotri, Irina Kerkis
Published 2011-12-01

MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling

by Hideyuki Nakashima, Keita Tsujimura, Koichiro Irie, Takuya Imamura, Cleber A. Trujillo, Masataka Ishizu, Masahiro Uesaka, Miao Pan, Hirofumi Noguchi, Kanako Okada, Kei Aoyagi, Tomoko Andoh-Noda, Hideyuki Okano, Alysson R. Muotri, Kinichi Nakashima
Published 2021-05-01

Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids

by Cleber A Trujillo, Jason W Adams, Priscilla D Negraes, Cassiano Carromeu, Leon Tejwani, Allan Acab, Ben Tsuda, Charles A Thomas, Neha Sodhi, Katherine M Fichter, Sarah Romero, Fabian Zanella, Terrence J Sejnowski, Henning Ulrich, Alysson R Muotri
Published 2021-01-01

Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease

by Jacqueline M. Ward, Colleen A. Stoyas, Pawel M. Switonski, Farid Ichou, Weiwei Fan, Brett Collins, Christopher E. Wall, Isaac Adanyeguh, Chenchen Niu, Bryce L. Sopher, Chizuru Kinoshita, Richard S. Morrison, Alexandra Durr, Alysson R. Muotri, Ronald M. Evans, Fanny Mochel, Albert R. La Spada
Published 2019-01-01

Brainstem Organoids From Human Pluripotent Stem Cells

by Nobuyuki Eura, Takeshi K. Matsui, Takeshi K. Matsui, Joachim Luginbühl, Masaya Matsubayashi, Hitoki Nanaura, Hitoki Nanaura, Tomo Shiota, Kaoru Kinugawa, Naohiko Iguchi, Takao Kiriyama, Canbin Zheng, Tsukasa Kouno, Yan Jun Lan, Pornparn Kongpracha, Pattama Wiriyasermkul, Yoshihiko M. Sakaguchi, Riko Nagata, Tomoya Komeda, Naritaka Morikawa, Fumika Kitayoshi, Miyong Jong, Shinko Kobashigawa, Mari Nakanishi, Masatoshi Hasegawa, Yasuhiko Saito, Takashi Shiromizu, Yuhei Nishimura, Takahiko Kasai, Maiko Takeda, Hiroshi Kobayashi, Yusuke Inagaki, Yasuhito Tanaka, Manabu Makinodan, Toshifumi Kishimoto, Hiroki Kuniyasu, Shushi Nagamori, Alysson R. Muotri, Alysson R. Muotri, Jay W. Shin, Kazuma Sugie, Eiichiro Mori
Published 2020-06-01

Species-specific maturation profiles of human, chimpanzee and bonobo neural cells

by Maria C Marchetto, Branka Hrvoj-Mihic, Bilal E Kerman, Diana X Yu, Krishna C Vadodaria, Sara B Linker, Iñigo Narvaiza, Renata Santos, Ahmet M Denli, Ana PD Mendes, Ruth Oefner, Jonathan Cook, Lauren McHenry, Jaeson M Grasmick, Kelly Heard, Callie Fredlender, Lynne Randolph-Moore, Rijul Kshirsagar, Rea Xenitopoulos, Grace Chou, Nasun Hah, Alysson R Muotri, Krishnan Padmanabhan, Katerina Semendeferi, Fred H Gage
Published 2019-02-01

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

by Kristen J. Brennand, M. Carol Marchetto, Nissim Benvenisty, Oliver Brüstle, Allison Ebert, Juan Carlos Izpisua Belmonte, Ajamete Kaykas, Madeline A. Lancaster, Frederick J. Livesey, Michael J. McConnell, Ronald D. McKay, Eric M. Morrow, Alysson R. Muotri, David M. Panchision, Lee L. Rubin, Akira Sawa, Frank Soldner, Hongjun Song, Lorenz Studer, Sally Temple, Flora M. Vaccarino, Jun Wu, Pierre Vanderhaeghen, Fred H. Gage, Rudolf Jaenisch
Published 2015-12-01