PI3K/Akt Pathway: The Indestructible Role of a Vintage Target as a Support to the Most Recent Immunotherapeutic Approaches

by Matteo Caforio, Emmanuel de Billy, Biagio De Angelis, Stefano Iacovelli, Concetta Quintarelli, Valeria Paganelli, Valentina Folgiero
Published 2021-08-01

Neuron-specific regulation of class I PI3K catalytic subunits and their dysfunction in brain disorders

by Christina eGross, Gary J Bassell
Published 2014-02-01

Mechanisms of Resistance to PI3K Inhibitors in Cancer: Adaptive Responses, Drug Tolerance and Cellular Plasticity

by Sarah Christine Elisabeth Wright, Natali Vasilevski, Violeta Serra, Jordi Rodon, Pieter Johan Adam Eichhorn
Published 2021-03-01

PI3K-mediated glioprotective effect of epidermal growth factor under oxidative stress conditions

by Zhi-Xiang Hu, Chun-Li Chen, Jia-Song Yang, Zhong-Lou Zhou, Zong-Ming Song, Zhao-Yang Wang
Published 2014-06-01

Structural Determinants of Isoform Selectivity in PI3K Inhibitors

by Michelle S. Miller, Philip E. Thompson, Sandra B. Gabelli
Published 2019-02-01

The PI3K/AKT Pathway Is Activated by HGF in NT2D1 Non-Seminoma Cells and Has a Role in the Modulation of Their Malignant Behavior

by Luisa Gesualdi, Erica Leonetti, Alessandra Cucina, Bianca Maria Scicchitano, Silvia Sorrentino, Maria Grazia Tarsitano, Andrea Isidori, Mariano Bizzarri, Antonio Filippini, Anna Riccioli, Marcella Cammarota, Vincenzo Gigantino, Giulia Ricci, Angela Catizone
Published 2020-11-01

Disseminated and Congenital Toxoplasmosis in a Mother and Child With Activated PI3-Kinase δ Syndrome Type 2 (APDS2): Case Report and a Literature Review of Toxoplasma Infections in...

by Djuro Karanovic, Ian C. Michelow, Anthony R. Hayward, Suk See DeRavin, Ottavia M. Delmonte, Michael E. Grigg, Adam Kerry Dobbs, Julie E. Niemela, Jennifer Stoddard, Zaid Alhinai, Natasha Rybak, Nancy Hernandez, Stefania Pittaluga, Sergio D. Rosenzweig, Gulbu Uzel, Luigi D. Notarangelo
Published 2019-02-01

The Role of PI3K/AKT and MAPK Signaling Pathways in Erythropoietin Signalization

by Zuzana Tóthová, Martina Šemeláková, Zuzana Solárová, Jana Tomc, Nataša Debeljak, Peter Solár
Published 2021-07-01

The Mechanisms Underlying PTEN Loss in Human Tumors Suggest Potential Therapeutic Opportunities

by Hyeyoun Chang, Zhenying Cai, Thomas M. Roberts
Published 2019-11-01

Editorial: Human Disorders of PI3K Biology

by Carrie L. Lucas, Stuart G. Tangye
Published 2020-11-01

Discovery of Novel Dual Extracellular Regulated Protein Kinases (ERK) and Phosphoinositide 3-Kinase (PI3K) Inhibitors as a Promising Strategy for Cancer Therapy

by Lingzhi Zhang, Qiurong Ju, Jinjin Sun, Lei Huang, Shiqi Wu, Shuping Wang, Yin Li, Zhe Guan, Qihua Zhu, Yungen Xu
Published 2020-12-01

Profile of buparlisib and its potential in the treatment of breast cancer: evidence to date

by Criscitiello C, Viale G, Curigliano G, Goldhirsch A
Published 2018-01-01

Revisiting PI3-kinase signalling in angiogenesis

by Piotr Kobialka, Mariona Graupera
Published 2019-12-01

Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions

by Tian Liu, Yiwei Wang, Yubing Wang, Andrew M. Chan
Published 2019-08-01

Pharmacological targeting of PI3K isoforms as a therapeutic strategy in chronic lymphocytic leukaemia

by Matthew D. Blunt, Andrew J. Steele
Published 2015-01-01

Peran Jalur Phosphatidyl-Inositol-3-kinase (PI3K) dalam Resistensi Kemoterapi pada Kanker

by Zanuar Abidin
Published 2018-01-01

The role of phosphoinositide 3-kinase subunits in chronic thyroiditis

by Wojciechowska-Durczynska Katarzyna, Krawczyk-Rusiecka Kinga, Cyniak-Magierska Anna, Zygmunt Arkadiusz, Sporny Stanisław, Lewinski Andrzej
Published 2012-12-01

Effect of platelet-rich plasma on implant bone defects in rabbits through the FAK/PI3K/AKT signaling pathway

by Liu Wei, Chen Ben, Zheng Youyang, Shi Yuehua, Shi Zhuojin
Published 2019-07-01

A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer

by Patrick Schöffski, Sara Cresta, Ingrid A. Mayer, Hans Wildiers, Silvia Damian, Steven Gendreau, Isabelle Rooney, Kari M. Morrissey, Jill M. Spoerke, Vivian W. Ng, Stina M. Singel, Eric Winer
Published 2018-09-01

The PI3Kδ Inhibitor Idelalisib Diminishes Platelet Function and Shows Antithrombotic Potential

by María N. Barrachina, Irene Izquierdo, Lidia Hermida-Nogueira, Luis A. Morán, Amparo Pérez, Ana B. Arroyo, Nuria García-Barberá, Rocío González-Conejero, Sara Troitiño, Johannes A. Eble, José Rivera, Constantino Martínez, María I. Loza, Eduardo Domínguez, Ángel García
Published 2021-03-01